Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   AAIS09_RS00885 Genome accession   NZ_CP154595
Coordinates   165766..166206 (-) Length   146 a.a.
NCBI ID   WP_000861973.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain serotype 4     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 160766..171206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAIS09_RS00860 (AAIS09_00855) - 161027..162313 (+) 1287 WP_000278876.1 response regulator transcription factor -
  AAIS09_RS00865 (AAIS09_00860) - 162365..162898 (+) 534 WP_000729030.1 ABC transporter permease -
  AAIS09_RS00870 (AAIS09_00865) nrdI 162976..163446 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  AAIS09_RS00875 (AAIS09_00870) - 163739..165001 (-) 1263 WP_125184685.1 NRAMP family divalent metal transporter -
  AAIS09_RS00880 (AAIS09_00875) - 165311..165769 (-) 459 WP_000745059.1 DUF3021 domain-containing protein -
  AAIS09_RS00885 (AAIS09_00880) brsR 165766..166206 (-) 441 WP_000861973.1 LytTR family DNA-binding domain-containing protein Regulator
  AAIS09_RS00890 (AAIS09_00885) - 166294..166419 (-) 126 WP_001813544.1 hypothetical protein -
  AAIS09_RS00895 (AAIS09_00890) hexB 166562..168511 (+) 1950 WP_061813407.1 DNA mismatch repair endonuclease MutL Machinery gene
  AAIS09_RS00900 (AAIS09_00895) ribE 168836..169303 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  AAIS09_RS00905 (AAIS09_00900) - 169304..170509 (-) 1206 WP_369917044.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  AAIS09_RS00910 (AAIS09_00905) ribE 170529..171164 (-) 636 WP_000493842.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17151.84 Da        Isoelectric Point: 5.9842

>NTDB_id=893427 AAIS09_RS00885 WP_000861973.1 165766..166206(-) (brsR) [Streptococcus pneumoniae strain serotype 4]
MKVELQISETYEEEKLIVQAPQPTEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=893427 AAIS09_RS00885 WP_000861973.1 165766..166206(-) (brsR) [Streptococcus pneumoniae strain serotype 4]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363