Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   R1Y14_RS09965 Genome accession   NZ_CP136899
Coordinates   1936544..1937203 (+) Length   219 a.a.
NCBI ID   WP_000565001.1    Uniprot ID   A0A0B7M7B9
Organism   Streptococcus pneumoniae strain ST62     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1931544..1942203
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1Y14_RS09940 (R1Y14_09940) - 1931849..1932166 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  R1Y14_RS09945 (R1Y14_09945) - 1932181..1933077 (-) 897 WP_000825667.1 PEP phosphonomutase -
  R1Y14_RS09950 (R1Y14_09950) - 1933080..1934342 (-) 1263 WP_000413342.1 PTS sugar transporter subunit IIC -
  R1Y14_RS09955 (R1Y14_09955) - 1934622..1935800 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  R1Y14_RS09960 (R1Y14_09960) - 1936028..1936474 (-) 447 WP_000155399.1 GNAT family N-acetyltransferase -
  R1Y14_RS09965 (R1Y14_09965) cclA/cilC 1936544..1937203 (+) 660 WP_000565001.1 A24 family peptidase Machinery gene
  R1Y14_RS09970 (R1Y14_09970) - 1937255..1938406 (-) 1152 WP_000481756.1 XRE family transcriptional regulator -
  R1Y14_RS09975 (R1Y14_09975) - 1938421..1939152 (-) 732 WP_000934017.1 hypothetical protein -
  R1Y14_RS09980 (R1Y14_09980) - 1939372..1939482 (+) 111 Protein_1937 prepilin peptidase -
  R1Y14_RS09985 (R1Y14_09985) trpA 1939454..1940230 (-) 777 WP_001127015.1 tryptophan synthase subunit alpha -
  R1Y14_RS09990 (R1Y14_09990) trpB 1940223..1941446 (-) 1224 WP_000331292.1 tryptophan synthase subunit beta -
  R1Y14_RS09995 (R1Y14_09995) - 1941424..1942023 (-) 600 WP_000169901.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24820.92 Da        Isoelectric Point: 7.2761

>NTDB_id=893267 R1Y14_RS09965 WP_000565001.1 1936544..1937203(+) (cclA/cilC) [Streptococcus pneumoniae strain ST62]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=893267 R1Y14_RS09965 WP_000565001.1 1936544..1937203(+) (cclA/cilC) [Streptococcus pneumoniae strain ST62]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
ATACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTACTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M7B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

98.174

100

0.982
  cclA/cilC Streptococcus pneumoniae Rx1

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae D39

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae R6

96.804

100

0.968
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872