Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   R1T10_RS01125 Genome accession   NZ_CP136807
Coordinates   212095..213360 (-) Length   421 a.a.
NCBI ID   WP_002244728.1    Uniprot ID   -
Organism   Neisseria meningitidis NMB     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 207095..218360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1T10_RS01115 yccS 207905..210055 (+) 2151 WP_017201245.1 YccS family putative transporter -
  R1T10_RS01120 - 210832..211116 (-) 285 WP_002216166.1 GIY-YIG nuclease family protein -
  R1T10_RS01125 pilA 212095..213360 (-) 1266 WP_002244728.1 signal recognition particle-docking protein FtsY Machinery gene
  R1T10_RS01130 msrAB 213505..215073 (+) 1569 WP_002216163.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  R1T10_RS01135 - 215175..215660 (-) 486 WP_002221794.1 CinA family protein -
  R1T10_RS01140 - 215686..216534 (-) 849 WP_002215243.1 mechanosensitive ion channel family protein -
  R1T10_RS01145 - 216628..217629 (-) 1002 WP_002223261.1 thiamine ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 421 a.a.        Molecular weight: 45215.53 Da        Isoelectric Point: 4.5585

>NTDB_id=892830 R1T10_RS01125 WP_002244728.1 212095..213360(-) (pilA) [Neisseria meningitidis NMB]
MFSFFRRKKKQETPAPEEAQVQETAAKAESEVTQIVENIKEEVESLTESVKGQVESAVETVSGAVEQVKEAVAEMLSEAE
EAAEKAAEQVEAAKEAIAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GESIDDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1266 bp        

>NTDB_id=892830 R1T10_RS01125 WP_002244728.1 212095..213360(-) (pilA) [Neisseria meningitidis NMB]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCCCGAGGAGGCTCAAGTTCAGGAAACTGCAGCAAA
AGCAGAATCCGAAGTTACTCAAATAGTTGAAAATATTAAAGAAGAAGTCGAATCTTTAACGGAAAGCGTCAAAGGGCAGG
TCGAATCGGCTGTTGAAACCGTCAGCGGTGCGGTTGAACAAGTAAAGGAAGCCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCATTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCAACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGACATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAAAAACCATTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGATACTTTCCGCGCCGCCGCCCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGTGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTG
GGCGAAAGCATAGACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(136-202)

SRP54-type protein, GTPase domain (SRP54)

(221-420)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

93.824

100

0.938