Detailed information NTG0891823

Bioinformatically predicted

Overview

• Name: uvrC
• Type: Machinery gene
• Locus tag: RZR97_RS03345
• Genome accession: NZ_CP136593
• Coordinates: 668438..670255 (-)
• Length: 605 a.a.
• NCBI ID: WP_317067480.1
• Uniprot ID: -
• Organism: Hydrogenimonas thermophila strain SWIR-21
• Function: integration of short DNA fragment (predicted from homology) DNA binding and uptake

Genomic Context

Location: 663438..675255

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RZR97_RS03325 (RZR97_03325)	-	664015..664767 (-)	753	WP_092911037.1	pyrroline-5-carboxylate reductase	-
RZR97_RS03330 (RZR97_03330)	fliW	664789..665193 (-)	405	WP_317067477.1	flagellar assembly protein FliW	-
RZR97_RS03335 (RZR97_03335)	-	665268..665915 (+)	648	WP_317067478.1	outer membrane protein assembly factor BamD	-
RZR97_RS03340 (RZR97_03340)	lon	665981..668404 (+)	2424	WP_317067479.1	endopeptidase La	-
RZR97_RS03345 (RZR97_03345)	uvrC	668438..670255 (-)	1818	WP_317067480.1	excinuclease ABC subunit UvrC	Machinery gene
RZR97_RS03350 (RZR97_03350)	-	670240..670686 (-)	447	WP_092911051.1	hypothetical protein	-
RZR97_RS03355 (RZR97_03355)	-	670797..672242 (+)	1446	WP_092911053.1	L-aspartate oxidase	-
RZR97_RS03360 (RZR97_03360)	nhaD	672269..673576 (+)	1308	WP_092911055.1	sodium:proton antiporter NhaD	-
RZR97_RS03365 (RZR97_03365)	guaA	673590..675134 (+)	1545	WP_092911057.1	glutamine-hydrolyzing GMP synthase	-

Sequence

Protein

• Length: 605 a.a.
• Molecular weight: 69871.73 Da
• Isoelectric Point: 9.7794

>NTDB_id=891823 RZR97_RS03345 WP_317067480.1 668438..670255(-) (uvrC) [Hydrogenimonas thermophila strain SWIR-21]
MLTTLKNLPDKPGVYQYFDKDRKLLYVGKAKSLKKRVKSYFRFTPELAPAQKLSPRIYNMVSQIAHIETIVTNSESDALL
LENSLIKQLRPKYNILLRDDKTYPYLYIDLSEPFARLELTRKVVKGNKVKYFGPFPNGSKAILSSIYELVPLVQKKSCIK
GKKACLFHQIKRCMAPCEGKISQKEYSKLIDEAIGYIHNKKALLTELEKRMEKYAEQLRFEEAAQIRDRIEAIKKIEEVS
TTDIAKLEDLDIFTVAFDETRGVVVRLFMREGKIVSSSHTYIEEIEEQIGEEEIEAIYRRTILEFYTAETPFTARSILTA
HSLSDRDELESILSERFGKRIHLHHPKRGEKKRLIDLGLQNATELLRQKRSKPQSDILERIKSLLNLTSKPTRVEVYDNS
HLMGTATVGAMVVYDNEKWDKASYRHYNLNAKDEYHQMQEMLTRRIESFSETPPPDLWVIDGGETLRVLAENLLKNAGVN
LPVVGVAKEKIDAKAHRAKGSAKDILYTEDGELRLQPTDTRLQWFQRLRDEAHRFAISFHKKQRLKKDKTISLLEVNGIG
PAKVKRLLDFFGTFEEIKKADFETLCSVVSSKDAKAIKDFFNNKK

Nucleotide

• Length: 1818 bp

>NTDB_id=891823 RZR97_RS03345 WP_317067480.1 668438..670255(-) (uvrC) [Hydrogenimonas thermophila strain SWIR-21]
ATGCTTACAACACTAAAAAACTTACCAGACAAACCAGGGGTATATCAATATTTCGATAAAGATAGAAAACTTCTTTATGT
AGGAAAAGCAAAATCACTTAAAAAGCGTGTAAAAAGCTACTTTAGGTTTACTCCTGAGTTGGCACCTGCTCAAAAACTTA
GTCCTAGAATCTACAATATGGTCTCACAAATTGCGCATATTGAGACAATAGTTACAAATAGTGAGAGCGATGCTCTTTTG
CTTGAAAATTCACTAATAAAGCAACTTAGACCAAAGTATAATATTCTTCTGCGTGATGATAAGACATACCCTTATCTCTA
TATTGATCTAAGTGAACCTTTTGCAAGATTGGAGTTAACACGTAAAGTAGTTAAAGGTAATAAAGTAAAATATTTTGGAC
CTTTTCCTAATGGATCAAAAGCTATTCTTTCATCTATTTATGAGCTTGTTCCATTAGTTCAAAAAAAATCTTGTATTAAG
GGTAAAAAGGCTTGTCTCTTTCATCAAATCAAACGGTGTATGGCTCCTTGTGAAGGGAAAATTAGTCAAAAAGAGTACTC
AAAACTCATAGATGAAGCTATCGGCTATATTCATAATAAAAAGGCTCTATTGACTGAACTTGAAAAGAGAATGGAAAAGT
ATGCTGAGCAACTTCGGTTTGAAGAGGCAGCACAGATTAGAGATCGTATAGAAGCAATTAAAAAAATTGAAGAGGTGAGC
ACTACAGATATAGCTAAACTTGAAGATTTAGATATATTCACCGTAGCTTTTGATGAGACAAGAGGGGTTGTAGTGCGTCT
CTTTATGAGAGAAGGAAAGATTGTATCATCAAGTCATACATATATTGAAGAGATAGAAGAGCAAATAGGTGAAGAAGAGA
TTGAGGCTATATATAGAAGAACTATACTAGAGTTTTACACAGCTGAGACACCTTTTACGGCTCGTTCTATCTTAACTGCT
CACAGCTTGAGTGATAGAGATGAACTTGAATCTATTTTATCTGAAAGATTTGGTAAACGCATACATTTGCACCACCCAAA
ACGTGGAGAGAAAAAACGTTTAATAGACCTTGGATTGCAAAATGCCACTGAACTTTTAAGACAGAAACGCAGCAAACCTC
AATCTGATATTCTTGAGCGTATTAAGTCACTTCTAAATCTTACTAGCAAACCTACACGTGTAGAAGTTTACGACAACTCA
CATTTGATGGGAACTGCTACAGTAGGAGCGATGGTGGTTTATGATAATGAGAAATGGGACAAAGCATCATATAGGCACTA
TAACTTAAATGCTAAAGATGAATATCATCAGATGCAAGAGATGTTAACAAGGCGAATAGAGTCATTTAGTGAAACACCAC
CTCCAGATTTATGGGTTATAGATGGTGGAGAGACATTAAGGGTATTGGCAGAGAATCTACTAAAAAATGCAGGAGTAAAC
CTTCCTGTTGTAGGAGTTGCAAAAGAGAAAATTGATGCAAAAGCCCACCGTGCAAAAGGTTCAGCAAAAGATATACTCTA
CACTGAAGATGGAGAATTAAGACTTCAACCAACCGATACACGTCTTCAATGGTTTCAGAGGCTACGTGATGAAGCCCATC
GTTTCGCAATATCATTTCATAAAAAACAGCGTCTTAAAAAAGATAAGACTATATCTTTACTTGAAGTTAATGGTATAGGG
CCAGCAAAAGTGAAACGGCTTTTAGACTTTTTTGGAACATTTGAAGAGATTAAGAAAGCAGACTTTGAAACACTATGCAG
TGTAGTATCTAGCAAAGATGCTAAGGCTATAAAAGATTTTTTTAATAACAAGAAGTAA

Domains

Predicted by InterproScan.

• UvrB/uvrC motif (UVR) (202-235)

• GIY-YIG catalytic domain (GIY-YIG) (12-94)

• Helix-hairpin-helix domain (HHH_5) (552-599)

• UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom) (383-537)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrC	Helicobacter pylori 26695	51.031	96.198	0.491