Detailed information NTG0891813

Bioinformatically predicted

Overview

• Name: uvrC
• Type: Machinery gene
• Locus tag: RZR91_RS03355
• Genome accession: NZ_CP136592
• Coordinates: 666514..668331 (-)
• Length: 605 a.a.
• NCBI ID: WP_317067480.1
• Uniprot ID: -
• Organism: Hydrogenimonas thermophila strain SWIR-17
• Function: integration of short DNA fragment (predicted from homology) DNA binding and uptake

Genomic Context

Location: 661514..673331

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RZR91_RS03335 (RZR91_03335)	-	662091..662843 (-)	753	WP_092911037.1	pyrroline-5-carboxylate reductase	-
RZR91_RS03340 (RZR91_03340)	fliW	662865..663269 (-)	405	WP_317067477.1	flagellar assembly protein FliW	-
RZR91_RS03345 (RZR91_03345)	-	663344..663991 (+)	648	WP_317067478.1	outer membrane protein assembly factor BamD	-
RZR91_RS03350 (RZR91_03350)	lon	664057..666480 (+)	2424	WP_317067479.1	endopeptidase La	-
RZR91_RS03355 (RZR91_03355)	uvrC	666514..668331 (-)	1818	WP_317067480.1	excinuclease ABC subunit UvrC	Machinery gene
RZR91_RS03360 (RZR91_03360)	-	668316..668762 (-)	447	WP_092911051.1	hypothetical protein	-
RZR91_RS03365 (RZR91_03365)	-	668873..670318 (+)	1446	WP_092911053.1	L-aspartate oxidase	-
RZR91_RS03370 (RZR91_03370)	nhaD	670345..671652 (+)	1308	WP_092911055.1	sodium:proton antiporter NhaD	-
RZR91_RS03375 (RZR91_03375)	guaA	671666..673210 (+)	1545	WP_092911057.1	glutamine-hydrolyzing GMP synthase	-

Sequence

Protein

• Length: 605 a.a.
• Molecular weight: 69871.73 Da
• Isoelectric Point: 9.7794

>NTDB_id=891813 RZR91_RS03355 WP_317067480.1 666514..668331(-) (uvrC) [Hydrogenimonas thermophila strain SWIR-17]
MLTTLKNLPDKPGVYQYFDKDRKLLYVGKAKSLKKRVKSYFRFTPELAPAQKLSPRIYNMVSQIAHIETIVTNSESDALL
LENSLIKQLRPKYNILLRDDKTYPYLYIDLSEPFARLELTRKVVKGNKVKYFGPFPNGSKAILSSIYELVPLVQKKSCIK
GKKACLFHQIKRCMAPCEGKISQKEYSKLIDEAIGYIHNKKALLTELEKRMEKYAEQLRFEEAAQIRDRIEAIKKIEEVS
TTDIAKLEDLDIFTVAFDETRGVVVRLFMREGKIVSSSHTYIEEIEEQIGEEEIEAIYRRTILEFYTAETPFTARSILTA
HSLSDRDELESILSERFGKRIHLHHPKRGEKKRLIDLGLQNATELLRQKRSKPQSDILERIKSLLNLTSKPTRVEVYDNS
HLMGTATVGAMVVYDNEKWDKASYRHYNLNAKDEYHQMQEMLTRRIESFSETPPPDLWVIDGGETLRVLAENLLKNAGVN
LPVVGVAKEKIDAKAHRAKGSAKDILYTEDGELRLQPTDTRLQWFQRLRDEAHRFAISFHKKQRLKKDKTISLLEVNGIG
PAKVKRLLDFFGTFEEIKKADFETLCSVVSSKDAKAIKDFFNNKK

Nucleotide

• Length: 1818 bp

>NTDB_id=891813 RZR91_RS03355 WP_317067480.1 666514..668331(-) (uvrC) [Hydrogenimonas thermophila strain SWIR-17]
ATGCTTACAACACTAAAAAACTTACCAGACAAACCAGGGGTATATCAATATTTCGATAAAGATAGAAAACTTCTTTATGT
AGGAAAAGCAAAATCACTTAAAAAGCGTGTAAAAAGCTACTTTAGGTTTACTCCTGAGTTGGCACCTGCTCAAAAACTTA
GTCCTAGAATCTACAATATGGTCTCACAAATTGCGCATATTGAGACAATAGTTACAAATAGTGAGAGCGATGCTCTTTTG
CTTGAAAATTCACTAATAAAGCAACTTAGACCAAAGTATAATATTCTTCTGCGTGATGATAAGACATACCCTTATCTCTA
TATTGATCTAAGTGAACCTTTTGCAAGATTGGAGTTAACACGTAAAGTAGTTAAAGGTAATAAAGTAAAATATTTTGGAC
CTTTTCCTAATGGATCAAAAGCTATTCTTTCATCTATTTATGAGCTTGTTCCATTAGTTCAAAAAAAATCTTGTATTAAG
GGTAAAAAGGCTTGTCTCTTTCATCAAATCAAACGGTGTATGGCTCCTTGTGAAGGGAAAATTAGTCAAAAAGAGTACTC
AAAACTCATAGATGAAGCTATCGGCTATATTCATAATAAAAAGGCTCTATTGACTGAACTTGAAAAGAGAATGGAAAAGT
ATGCTGAGCAACTTCGGTTTGAAGAGGCAGCACAGATTAGAGATCGTATAGAAGCAATTAAAAAAATTGAAGAGGTGAGC
ACTACAGATATAGCTAAACTTGAAGATTTAGATATATTCACCGTAGCTTTTGATGAGACAAGAGGGGTTGTAGTGCGTCT
CTTTATGAGAGAAGGAAAGATTGTATCATCAAGTCATACATATATTGAAGAGATAGAAGAGCAAATAGGTGAAGAAGAGA
TTGAGGCTATATATAGAAGAACTATACTAGAGTTTTACACAGCTGAGACACCTTTTACGGCTCGTTCTATCTTAACTGCT
CACAGCTTGAGTGATAGAGATGAACTTGAATCTATTTTATCTGAAAGATTTGGTAAACGCATACATTTGCACCACCCAAA
ACGTGGAGAGAAAAAACGTTTAATAGACCTTGGATTGCAAAATGCCACTGAACTTTTAAGACAGAAACGCAGCAAACCTC
AATCTGATATTCTTGAGCGTATTAAGTCACTTCTAAATCTTACTAGCAAACCTACACGTGTAGAAGTTTACGACAACTCA
CATTTGATGGGAACTGCTACAGTAGGAGCGATGGTGGTTTATGATAATGAGAAATGGGACAAAGCATCATATAGGCACTA
TAACTTAAATGCTAAAGATGAATATCATCAGATGCAAGAGATGTTAACAAGGCGAATAGAGTCATTTAGTGAAACACCAC
CTCCAGATTTATGGGTTATAGATGGTGGAGAGACATTAAGGGTATTGGCAGAGAATCTACTAAAAAATGCAGGAGTAAAC
CTTCCTGTTGTAGGAGTTGCAAAAGAGAAAATTGATGCAAAAGCCCACCGTGCAAAAGGTTCAGCAAAAGATATACTCTA
CACTGAAGATGGAGAATTAAGACTTCAACCAACCGATACACGTCTTCAATGGTTTCAGAGGCTACGTGATGAAGCCCATC
GTTTCGCAATATCATTTCATAAAAAACAGCGTCTTAAAAAAGATAAGACTATATCTTTACTTGAAGTTAATGGTATAGGG
CCAGCAAAAGTGAAACGGCTTTTAGACTTTTTTGGAACATTTGAAGAGATTAAGAAAGCAGACTTTGAAACACTATGCAG
TGTAGTATCTAGCAAAGATGCTAAGGCTATAAAAGATTTTTTTAATAACAAGAAGTAA

Domains

Predicted by InterproScan.

• UvrB/uvrC motif (UVR) (202-235)

• GIY-YIG catalytic domain (GIY-YIG) (12-94)

• Helix-hairpin-helix domain (HHH_5) (552-599)

• UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom) (383-537)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrC	Helicobacter pylori 26695	51.031	96.198	0.491