Detailed information NTG0891386

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: RZS16_RS14000
• Genome accession: NZ_CP136524
• Coordinates: 2774628..2775515 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain BAA-1556_Catania_SCV
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2769628..2780515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RZS16_RS13970 (RZS16_13965)	-	2769647..2769739 (+)	93	WP_010956583.1	hypothetical protein	-
RZS16_RS13975 (RZS16_13970)	-	2769847..2770344 (-)	498	WP_001065268.1	glutathione peroxidase	-
RZS16_RS13980 (RZS16_13975)	-	2770354..2770614 (-)	261	WP_001789910.1	hypothetical protein	-
RZS16_RS13985 (RZS16_13980)	-	2770996..2771109 (-)	114	WP_001791776.1	hypothetical protein	-
RZS16_RS13990 (RZS16_13985)	-	2771768..2773768 (-)	2001	WP_000776751.1	ABC transporter permease	-
RZS16_RS13995 (RZS16_13990)	-	2773765..2774520 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
RZS16_RS14000 (RZS16_13995)	braS	2774628..2775515 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
RZS16_RS14005 (RZS16_14000)	braR	2775526..2776191 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
RZS16_RS14010 (RZS16_14005)	-	2776217..2776417 (-)	201	WP_000604728.1	hypothetical protein	-
RZS16_RS14015 (RZS16_14010)	-	2776615..2778039 (+)	1425	WP_000953744.1	alkaline phosphatase	-
RZS16_RS14720	-	2778099..2778200 (-)	102	WP_000731972.1	SE2200 family small protein	-
RZS16_RS14025 (RZS16_14020)	-	2778322..2778777 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
RZS16_RS14030 (RZS16_14025)	-	2779022..2779783 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=891386 RZS16_RS14000 WP_000143419.1 2774628..2775515(-) (braS) [Staphylococcus aureus strain BAA-1556_Catania_SCV]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=891386 RZS16_RS14000 WP_000143419.1 2774628..2775515(-) (braS) [Staphylococcus aureus strain BAA-1556_Catania_SCV]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997