Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   AAGG05_RS20870 Genome accession   NZ_CP151934
Coordinates   4244166..4244822 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 8178 isolate T4048     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4239166..4249822
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAGG05_RS20840 (AAGG05_20830) yecA 4240418..4241083 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  AAGG05_RS20860 (AAGG05_20850) pgsA 4241732..4242280 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  AAGG05_RS20865 (AAGG05_20855) uvrC 4242337..4244169 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  AAGG05_RS20870 (AAGG05_20860) letA 4244166..4244822 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  AAGG05_RS20875 (AAGG05_20865) yecU 4245118..4245294 (+) 177 WP_001307856.1 protein YecU -
  AAGG05_RS20880 (AAGG05_20870) yecF 4245281..4245505 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  AAGG05_RS20885 (AAGG05_20875) sdiA 4245573..4246295 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  AAGG05_RS20890 (AAGG05_20880) tcyN 4246525..4247277 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  AAGG05_RS20895 (AAGG05_20885) tcyL 4247274..4247942 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  AAGG05_RS20900 (AAGG05_20890) dcyD 4247957..4248943 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=891309 AAGG05_RS20870 WP_000611328.1 4244166..4244822(-) (letA) [Escherichia coli strain 8178 isolate T4048]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=891309 AAGG05_RS20870 WP_000611328.1 4244166..4244822(-) (letA) [Escherichia coli strain 8178 isolate T4048]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCTACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTTAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482