Detailed information NTG0887024

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: RSK81_RS03315
• Genome accession: NZ_CP135591
• Coordinates: 647221..649491 (-)
• Length: 756 a.a.
• NCBI ID: WP_315687419.1
• Uniprot ID: A0AA96NTU5
• Organism: Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 642221..654491

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RSK81_RS03285 (RSK81_03285)	-	643617..644072 (-)	456	WP_223312271.1	MarR family winged helix-turn-helix transcriptional regulator	-
RSK81_RS03290 (RSK81_03290)	-	644095..644529 (+)	435	WP_315687414.1	GNAT family N-acetyltransferase	-
RSK81_RS03295 (RSK81_03295)	-	644555..644857 (-)	303	WP_002896152.1	DUF1827 family protein	-
RSK81_RS03300 (RSK81_03300)	-	644925..645374 (-)	450	WP_002896150.1	NUDIX hydrolase	-
RSK81_RS03305 (RSK81_03305)	-	645599..646498 (+)	900	WP_315687416.1	YafY family protein	-
RSK81_RS03310 (RSK81_03310)	-	646558..647172 (+)	615	WP_315687417.1	GyrI-like domain-containing protein	-
RSK81_RS03315 (RSK81_03315)	clpE	647221..649491 (-)	2271	WP_315687419.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
RSK81_RS03320 (RSK81_03320)	-	649741..649971 (+)	231	WP_002896146.1	DUF1797 family protein	-
RSK81_RS03325 (RSK81_03325)	-	650161..651015 (+)	855	WP_002902603.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
RSK81_RS03330 (RSK81_03330)	-	651012..651775 (+)	764	Protein_634	HAD hydrolase family protein	-
RSK81_RS03335 (RSK81_03335)	-	651883..652725 (+)	843	WP_268697764.1	NAD(P)H-hydrate dehydratase	-
RSK81_RS03340 (RSK81_03340)	-	652701..652936 (+)	236	Protein_636	initiator RepB protein	-
RSK81_RS03345 (RSK81_03345)	xseA	652881..654221 (+)	1341	WP_268697763.1	exodeoxyribonuclease VII large subunit	-
RSK81_RS03350 (RSK81_03350)	-	654199..654411 (+)	213	WP_002896137.1	exodeoxyribonuclease VII small subunit	-

Sequence

Protein

• Length: 756 a.a.
• Molecular weight: 83612.68 Da
• Isoelectric Point: 5.0142

>NTDB_id=887024 RSK81_RS03315 WP_315687419.1 647221..649491(-) (clpE) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
MLCQNCKINESTIHLYTNVNGHKQQVDLCQNCYQIMKTDPEHSLFGGIANANNHGTDPIDDFFNSLSNFQQPQEPPTPPT
QSGGAYGGGGGYGSNPSKGGQPQPSPQKPKGLLEEFGINVTELARRGEIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLSQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLIDEIRSRQDVILFIDEIHEIVGAGSA
GDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDAA
IEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEL
QQTSVLDKDTPIISEKTIEHIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGSPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTERVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFQALSKDNLLQIVNLMLDDVNQRLATNDIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLENP
SEKGLKAIMTSNGKILIKSAKKTESTESVNSSQEEK

Nucleotide

• Length: 2271 bp

>NTDB_id=887024 RSK81_RS03315 WP_315687419.1 647221..649491(-) (clpE) [Streptococcus sp. DTU_2020_1000888_1_SI_GRL_NUU_041A]
ATGCTTTGCCAAAATTGTAAAATCAATGAATCTACGATTCACCTTTATACCAACGTAAATGGCCATAAACAGCAGGTGGA
TTTGTGCCAAAACTGCTACCAAATCATGAAAACAGATCCTGAACATTCCTTGTTCGGCGGAATCGCTAATGCCAACAATC
ACGGAACAGACCCTATCGATGACTTCTTCAACAGCCTCAGCAATTTCCAACAGCCTCAGGAACCGCCTACTCCTCCTACC
CAATCTGGCGGAGCCTATGGAGGCGGTGGCGGCTACGGTTCCAATCCTAGCAAGGGTGGTCAGCCTCAGCCAAGTCCGCA
AAAGCCAAAAGGCCTGCTGGAAGAGTTTGGTATCAACGTGACTGAGTTGGCTCGCCGAGGCGAGATTGACCCTGTTATTG
GCCGTGATGAAGAAATCGTCCGTGTCATTGAAATCCTCAACCGCCGCACCAAAAACAATCCTGTTCTTATCGGAGAGCCA
GGAGTCGGAAAAACTGCCGTGGTGGAAGGCTTGTCCCAAAAAATTGTTGATGGTGATGTGCCTCATAAACTCCAAGGCAA
GGAAGTTATCCGCCTAGACGTTGTCAGCTTAGTGCAGGGAACTGGTATCCGTGGCCAATTTGAGGAACGGATGCAGAAGC
TCATTGATGAGATTCGTTCTCGTCAGGATGTCATTCTCTTTATTGATGAAATCCATGAAATTGTCGGAGCAGGCTCTGCT
GGCGATGGCAATATGGACGCTGGGAACATCCTCAAACCAGCTCTGGCTCGCGGAGAACTCCAGATGGTTGGAGCAACCAC
CCTTAATGAATACCGTATCATCGAGAAGGATGCTGCACTGGAGCGCCGGATGCAGCCCGTTAAGGTAGACGAGCCGACGG
TAGAGGAAACGATTACCATCCTCAAAGGGATTCAGAAAAAATACGAAGACTACCATCACGTCAAGTACACGGATGCGGCC
ATTGAAGCGGCTGCCCTTCTCTCCAACCGCTACATTCAAGATCGCTTCCTGCCAGACAAGGCTATTGACCTCTTGGATGA
GGCTGGATCCAAGATGAATCTGACCCTCAACTTCGTTGATCCCAAAGTCATTGACCAACGTCTGATTGAGGCTGAAAACC
TCAAGGCTCAGGCAACCCGTGACGAAGATTTCGAGAAAGCAGCTTACTTCCGTGACCAGATTGCCAAGTACAAGGAACTC
CAGCAGACAAGTGTACTAGACAAGGATACTCCGATTATCAGCGAGAAAACGATTGAGCACATTGTAGAGCAAAAAACCAA
TATCCCAGTTGGCGACCTCAAAGAAAAGGAACAGTCTCAGCTGGTCAATCTTGCCAGTGACTTAAAGGCCCATGTCATCG
GCCAAGACGATGCTGTGGATAAGATTGCCAAGGCCATCCGCCGCAACCGGGTCGGACTGGGAAGTCCTAATCGCCCAATC
GGCAGCTTCCTCTTTGTCGGACCTACTGGTGTCGGTAAGACTGAGCTGTCTAAGCAACTAGCCATTGAGCTATTTGGCTC
GGCTGACAGTATGATTCGCTTTGATATGAGTGAATACATGGAGAAACACAGCGTGGCCAAGCTGGTCGGTGCCCCTCCGG
GCTATGTTGGCTATGATGAAGCTGGTCAATTGACTGAGCGCGTCCGCCGCAATCCCTACTCACTCATTCTGCTGGATGAG
GTAGAAAAGGCCCATCCCGATGTTATGCACATGTTCCTACAGGTTCTAGATGATGGCCGCCTGACCGATGGTCAAGGCCG
GACTGTTAGCTTCAAGGACACCATTATCATCATGACATCCAATGCCGGAACCGGCAAAGCTGAAGCCAGTGTCGGCTTTG
GGGCAGCGCGTGAAGGCCGCACCAACTCCGTTTTGGGTGAATTAGGGAACTTCTTCAGTCCTGAGTTTATGAACCGCTTT
GACGGCATTATCGAATTCCAGGCGCTCAGCAAGGACAATCTGCTGCAAATCGTCAACCTGATGCTGGACGATGTCAATCA
ACGTTTGGCAACCAACGACATTCATCTGGATGTTACGGAGAAGGTCAAGGAAAAATTGGTCGATCTGGGCTACGATCCAA
AAATGGGCGCTCGCCCATTGCGCCGTACCATTCAGGACCATATCGAAGATGCTATTACTGACTTCTATCTGGAAAATCCA
AGCGAAAAAGGTCTCAAAGCTATCATGACCAGCAATGGCAAGATTCTCATCAAGTCAGCAAAGAAAACTGAAAGTACAGA
GTCAGTTAATTCATCACAAGAAGAAAAATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (293-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (478-641)

• ATPase family associated with various cellular activities (AAA) (AAA) (155-274)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (649-725)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	86.394	100	0.865
clpE	Streptococcus pneumoniae D39	86.394	100	0.865
clpE	Streptococcus pneumoniae R6	86.394	100	0.865
clpE	Streptococcus pneumoniae TIGR4	86.262	100	0.864
clpE	Streptococcus mutans UA159	83.841	99.868	0.837
clpC	Lactococcus lactis subsp. cremoris KW2	76.627	99.603	0.763
clpC	Bacillus subtilis subsp. subtilis str. 168	48.821	95.37	0.466
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.678	85.45	0.407
clpC	Streptococcus pneumoniae Rx1	48.47	82.143	0.398
clpC	Streptococcus pneumoniae D39	48.47	82.143	0.398
clpC	Streptococcus pneumoniae TIGR4	48.309	82.143	0.397
clpC	Streptococcus thermophilus LMD-9	47.284	82.804	0.392
clpC	Streptococcus thermophilus LMG 18311	46.965	82.804	0.389
clpC	Streptococcus mutans UA159	46.445	83.73	0.389