Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   RRU92_RS08535 Genome accession   NZ_CP135436
Coordinates   1783512..1785764 (+) Length   750 a.a.
NCBI ID   WP_315639371.1    Uniprot ID   A0AA96MQJ9
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1778512..1790764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS08515 (RRU92_08515) - 1780284..1781138 (-) 855 WP_315639369.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  RRU92_RS08520 (RRU92_08520) - 1781271..1782005 (-) 735 WP_045762888.1 amino acid ABC transporter ATP-binding protein -
  RRU92_RS08525 (RRU92_08525) - 1782005..1782688 (-) 684 WP_315639370.1 amino acid ABC transporter permease -
  RRU92_RS08530 (RRU92_08530) - 1782885..1783115 (+) 231 WP_000443576.1 DUF1797 family protein -
  RRU92_RS08535 (RRU92_08535) clpE 1783512..1785764 (+) 2253 WP_315639371.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  RRU92_RS08540 (RRU92_08540) - 1785853..1786302 (+) 450 WP_315639373.1 NUDIX hydrolase -
  RRU92_RS08545 (RRU92_08545) - 1786366..1786665 (+) 300 WP_060955508.1 DUF1827 family protein -
  RRU92_RS08550 (RRU92_08550) - 1786892..1787524 (+) 633 WP_315639374.1 GNAT family N-acetyltransferase -
  RRU92_RS08555 (RRU92_08555) metK 1787558..1788748 (-) 1191 WP_000003967.1 methionine adenosyltransferase -
  RRU92_RS08560 (RRU92_08560) - 1788987..1789685 (-) 699 WP_281334624.1 GntR family transcriptional regulator -

Sequence

Protein


Download         Length: 750 a.a.        Molecular weight: 83577.74 Da        Isoelectric Point: 4.9754

>NTDB_id=886557 RRU92_RS08535 WP_315639371.1 1783512..1785764(+) (clpE) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MLCQNCKINDSTIHLYTNLNGQQKQIDLCQNCYKIIKTDPNNSLFKGITDLNNRDFDPFGDFFNDLNNFRPSSNNNNIPP
TQSGGGYGGNGGYGSQNRGPAQTPPPIQEKGLLDEYGINVTEIARRGNIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRDREDVILFIDEIHEIVGAGSA
GEGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETIIILKGIQKKYEDYHHVHYTDGA
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEM
QKTKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLINLADDLKSHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKENLLQIVDLMLDDVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENP
SEKNLKAVMTSNGKIMIKSKNKLETVDSND

Nucleotide


Download         Length: 2253 bp        

>NTDB_id=886557 RRU92_RS08535 WP_315639371.1 1783512..1785764(+) (clpE) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGCTCTGTCAAAACTGTAAAATCAATGACTCAACGATTCATCTTTATACCAATCTCAATGGACAACAAAAGCAAATCGA
CCTTTGTCAAAATTGCTACAAAATTATCAAAACAGATCCTAACAATAGCTTATTCAAGGGCATTACAGATTTAAACAACC
GTGATTTTGATCCATTTGGAGACTTCTTTAACGATCTCAACAACTTTAGACCTTCTTCTAATAACAACAATATCCCCCCA
ACCCAGTCAGGGGGTGGATACGGTGGAAATGGTGGCTATGGTTCCCAAAATCGTGGTCCTGCCCAAACCCCACCACCAAT
CCAGGAAAAAGGACTCTTGGATGAATATGGTATCAATGTCACTGAGATTGCCCGTCGTGGAAATATTGACCCTGTAATTG
GCCGTGACGAAGAGATTATCCGTGTCATTGAAATCCTCAACCGCAGAACAAAAAACAACCCTGTCCTCATCGGTGAGCCT
GGTGTTGGTAAGACAGCCGTTGTAGAAGGTTTAGCTCAGAAAATTGTTGACGGTGATGTTCCACATAAGCTTCAAGGGAA
AGAAGTGATCCGCTTAGATGTCGTTAGCCTTGTTCAAGGAACAGGTATCCGAGGTCAGTTTGAAGAGCGCATGCAAAAAC
TCATGGAAGAAATTCGTGATCGCGAGGATGTTATCCTCTTTATCGACGAAATTCATGAGATTGTCGGTGCTGGTTCAGCA
GGAGAAGGGAATATGGATGCAGGAAATATCCTAAAACCAGCTCTTGCTCGTGGCGAACTCCAGTTAGTAGGTGCTACTAC
TCTCAATGAATACCGTATCATTGAAAAAGACGCTGCCCTTGAGCGCCGTATGCAGCCTGTTAAGGTAGATGAACCAACTG
TTGAAGAAACCATTATTATTCTTAAGGGGATTCAAAAGAAATACGAAGATTATCACCACGTTCATTATACTGATGGGGCT
ATCGAAGCGGCCGCTACTCTTTCTAATCGCTACATCCAAGACCGTTTCTTGCCAGACAAGGCTATTGACCTTCTAGATGA
AGCTGGTTCAAAAATGAACTTAACCTTGAATTTTGTAGATCCTAAGGTCATCGACCAACGCTTAATCGAGGCAGAAAATC
TCAAGGCACAAGCAACCCGCGATGAAGATTTTGAAAAAGCAGCCTACTTCCGTGACCAGATTGCCAAATATAAGGAAATG
CAAAAGACCAAGGTAACAGATCAGGATACTCCAATCATCAGTGAAAAGACAATCGAACACATCATCGAGCAAAAGACTAA
TATTCCAGTTGGTGATTTGAAAGAAAAAGAACAGTCTCAACTTATCAATCTAGCAGATGACCTCAAGTCTCATGTTATTG
GCCAAGACGATGCAGTAGATAAGATTGCTAAGGCTATCCGTCGTAACCGTGTTGGTTTAGGTACTCCAAACCGTCCAATT
GGTAGCTTCCTCTTTGTTGGTCCTACCGGTGTCGGTAAGACAGAACTTTCTAAACAACTGGCCATCGAACTCTTTGGTTC
TGCTGATAGCATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGCGTTGCTAAACTCGTTGGTGCCCCTCCGG
GATACGTAGGTTATGATGAAGCTGGACAATTGACTGAAAAAGTTCGTCGTAACCCCTACTCACTGATCCTCCTAGACGAG
GTTGAAAAAGCCCATCCAGATGTTATGCATATGTTCCTCCAAGTCTTGGATGATGGCCGTTTAACGGATGGTCAAGGTCG
CACTGTTAGCTTTAAAGATGCCATCATTATCATGACCTCAAATGCAGGTACAGGTAAGGCAGAAGCTAGTGTTGGATTTG
GTGCTGCTAGAGAAGGCCGTACTAACTCTGTCCTTGGGGAATTAGGCAACTTCTTTAGTCCAGAATTTATGAACCGTTTT
GATGGCATTATCGAATTCAAGGCTCTCAGCAAGGAAAATCTCCTTCAAATCGTTGACCTCATGTTAGATGATGTCAATAA
ACGACTCTCCAGTAATAACATCCATTTAGATGTGACAGATAAGGTTAAGGAGAAACTCGTAGACCTTGGCTACGATCCAA
AAATGGGAGCTCGCCCGCTTCGTCGTACAATCCAAGATTATATCGAAGATGCGATTACGGACTACTACCTTGAAAATCCA
AGCGAGAAAAACCTCAAAGCCGTCATGACTAGCAATGGTAAAATCATGATTAAATCAAAAAATAAATTGGAAACAGTTGA
CTCAAATGACTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(649-724)

AAA lid domain (AAA_lid_9)

(293-390)

AAA domain (Cdc48 subfamily) (AAA_2)

(478-641)

ATPase family associated with various cellular activities (AAA) (AAA)

(155-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

94.251

99.733

0.94
  clpE Streptococcus pneumoniae D39

94.251

99.733

0.94
  clpE Streptococcus pneumoniae R6

94.251

99.733

0.94
  clpE Streptococcus pneumoniae TIGR4

94.118

99.733

0.939
  clpE Streptococcus mutans UA159

83.845

99.867

0.837
  clpC Lactococcus lactis subsp. cremoris KW2

76.09

100

0.768
  clpC Bacillus subtilis subsp. subtilis str. 168

50.933

92.933

0.473
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.531

86.4

0.411
  clpC Streptococcus pneumoniae TIGR4

47.134

83.733

0.395
  clpC Streptococcus pneumoniae Rx1

47.134

83.733

0.395
  clpC Streptococcus pneumoniae D39

47.134

83.733

0.395
  clpC Streptococcus thermophilus LMD-9

46.955

83.2

0.391
  clpC Streptococcus thermophilus LMG 18311

46.635

83.2

0.388
  clpC Streptococcus mutans UA159

46.178

83.733

0.387