Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   RNZ43_RS06225 Genome accession   NZ_CP135143
Coordinates   1179517..1180173 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain L33a     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1174517..1185173
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RNZ43_RS06200 oppF 1175047..1175964 (+) 918 WP_416406238.1 oligopeptide ABC transporter ATP-binding protein OppF -
  RNZ43_RS06205 - 1176070..1177257 (+) 1188 WP_416406239.1 putative glycoside hydrolase -
  RNZ43_RS06210 - 1177375..1177953 (+) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  RNZ43_RS06215 spx 1178132..1178527 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  RNZ43_RS06220 - 1178585..1179241 (-) 657 WP_003155033.1 TerC family protein -
  RNZ43_RS06225 mecA 1179517..1180173 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  RNZ43_RS06230 - 1180324..1181484 (+) 1161 WP_094247076.1 competence protein CoiA family protein -
  RNZ43_RS06235 pepF 1181712..1183541 (+) 1830 WP_416406398.1 oligoendopeptidase F Regulator
  RNZ43_RS06240 - 1183579..1183746 (-) 168 WP_003155026.1 hypothetical protein -
  RNZ43_RS06245 spxH 1184032..1184934 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=885578 RNZ43_RS06225 WP_003155032.1 1179517..1180173(+) (mecA) [Bacillus velezensis strain L33a]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=885578 RNZ43_RS06225 WP_003155032.1 1179517..1180173(+) (mecA) [Bacillus velezensis strain L33a]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895