Detailed information NTG0885366

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: QN329_RS02460
• Genome accession: NZ_CP135103
• Coordinates: 414285..415514 (-)
• Length: 409 a.a.
• NCBI ID: WP_000728357.1
• Uniprot ID: A0AAD2WWM9
• Organism: Streptococcus agalactiae strain HU36/21
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 409285..420514

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QN329_RS02435 (QN329_02435)	-	409395..409592 (-)	198	WP_000285199.1	DUF951 domain-containing protein	-
QN329_RS02440 (QN329_02440)	-	409602..410495 (-)	894	WP_000987447.1	diacylglycerol/lipid kinase family protein	-
QN329_RS02445 (QN329_02445)	dnaN	410553..411689 (-)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
QN329_RS02450 (QN329_02450)	dnaA	411844..413205 (-)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
QN329_RS02455 (QN329_02455)	spo0J	413414..414187 (-)	774	WP_000456085.1	ParB/RepB/Spo0J family partition protein	Regulator
QN329_RS02460 (QN329_02460)	htrA	414285..415514 (-)	1230	WP_000728357.1	S1C family serine protease	Regulator
QN329_RS02465 (QN329_02465)	rlmH	415715..416194 (+)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
QN329_RS02485 (QN329_02485)	-	416774..419353 (-)	2580	WP_371105738.1	YfhO family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43090.54 Da
• Isoelectric Point: 9.5271

>NTDB_id=885366 QN329_RS02460 WP_000728357.1 414285..415514(-) (htrA) [Streptococcus agalactiae strain HU36/21]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVASPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=885366 QN329_RS02460 WP_000728357.1 414285..415514(-) (htrA) [Streptococcus agalactiae strain HU36/21]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGCATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGGGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTAACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.359	96.088	0.609
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.533	97.311	0.55
htrA	Streptococcus pneumoniae TIGR4	55.037	99.511	0.548
htrA	Streptococcus pneumoniae Rx1	55.037	99.511	0.548
htrA	Streptococcus pneumoniae D39	55.037	99.511	0.548
htrA	Streptococcus pneumoniae R6	55.037	99.511	0.548