Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   MGAS38345_RS03180 Genome accession   NZ_CP151437
Coordinates   619156..622788 (+) Length   1210 a.a.
NCBI ID   WP_032459868.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS38345     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 614156..627788
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS38345_RS03170 (MGAS38345_01298) - 614876..615793 (-) 918 WP_011285474.1 neutral zinc metallopeptidase -
  MGAS38345_RS03175 (MGAS38345_01300) rexB 615944..619159 (+) 3216 WP_010922126.1 ATP-dependent nuclease subunit B Machinery gene
  MGAS38345_RS03180 (MGAS38345_01302) rexA 619156..622788 (+) 3633 WP_032459868.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  MGAS38345_RS03185 (MGAS38345_01304) - 622928..623740 (+) 813 WP_002990394.1 transporter substrate-binding domain-containing protein -
  MGAS38345_RS03190 (MGAS38345_01306) rpsU 623881..624057 (+) 177 WP_000048058.1 30S ribosomal protein S21 -
  MGAS38345_RS03195 (MGAS38345_01308) mscL 624185..624547 (-) 363 WP_002990299.1 large conductance mechanosensitive channel protein MscL -
  MGAS38345_RS03200 (MGAS38345_01310) dnaG 624678..626492 (+) 1815 WP_011285477.1 DNA primase -
  MGAS38345_RS03205 (MGAS38345_01312) rpoD 626501..627610 (+) 1110 WP_027969234.1 RNA polymerase sigma factor RpoD -

Sequence

Protein


Download         Length: 1210 a.a.        Molecular weight: 139010.19 Da        Isoelectric Point: 6.6417

>NTDB_id=885152 MGAS38345_RS03180 WP_032459868.1 619156..622788(+) (rexA) [Streptococcus pyogenes strain MGAS38345]
MISFAPFLSPEAIKHLQENERCRDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTF
TVKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVL
KQEVFSKLFNEFMNQKEAPVFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHD
IELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDV
TVSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFSLLEQLQDFVLAFSEAYLAVKIQESAFEFSDIAHFAIKILEENTDI
RQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKPEQGKVILLKENF
RSQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEGISFSEVTIVAK
EIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRS
PMFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAHPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFN
DRFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVATPKQAVNLMTIHKSKGLQ
FPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEEMRLLYV
AMTRAEKKVYFIGKASKSKSQEITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKATYEPLLEPIGVDIIEKSSRSLSDFTL
PHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYR
EAPFAILKLDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLM
GGGKPEIVEV

Nucleotide


Download         Length: 3633 bp        

>NTDB_id=885152 MGAS38345_RS03180 WP_032459868.1 619156..622788(+) (rexA) [Streptococcus pyogenes strain MGAS38345]
GTGATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACATTTGCAAGAAAACGAAAGGTGCAGAGATCAGTCTCA
AAAACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCCAAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAA
AAACCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGAGGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTT
ACTGTTAAAGCAGCTACAGAACTGCGTGAGCGGATTGAAAACAAATTATACTCACAAATTGCTCAAACTACAGATTTTCA
AATGAAAGTTTATTTAACAGAACAATTGCAATCTCTTTGTCAAGCTGATATTGGTACTATGGATGCTTTTGCACAGAAAG
TAGTAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTTCGTATCATGCAGGATAAAGCAGAACAAGATGTTTTA
AAGCAAGAGGTGTTTAGCAAACTCTTTAATGAGTTTATGAATCAAAAAGAGGCACCGGTGTTTAGGGCTCTTGTGAAAAA
TTTTTCTGGTAACTGTAAAGACACTTCAGCTTTTAGAGAGTTAGTTTATACTTGTTATTCTTTTAGCCAATCGACAGAAA
ACCCAAAAATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAAACTTACCAAAGACTTGAAGATATCCCGGATCATGAT
ATTGAACTCTTACTTTTGGCAATGCAAGACACTGCAAATCAGCTAAGAGATGTGACTGATATGGAAGATTATGGGCAGCT
GACTAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAACGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATT
TTAAATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGAGATGTGACAGGCCTTATACCATCTGGGAATGATGTT
ACAGTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCAAAAATTAAAACAATTTAGGCATTTAGAAACAATTTT
AATGTATCAGAAAGACTGTTTTTCCTTATTGGAACAGTTACAAGATTTTGTGCTTGCGTTTTCAGAAGCTTATTTAGCTG
TCAAAATACAAGAAAGTGCTTTTGAATTTTCAGATATTGCACACTTTGCAATCAAAATTTTAGAGGAAAATACGGATATT
CGCCAATCCTATCAGCAACACTATCATGAGGTGATGGTTGATGAATATCAAGATAACAATCATATGCAAGAGCGACTCCT
GACCTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATATCAAACAATCGATCTATCGATTTCGGCAAGCCGATC
CTCAGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAACCTGAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTT
CGTAGCCAATCAGAGGTGTTAAATGTCAGCAATGCTGTTTTTAGTCACTTAATGGACGAATCAGTAGGAGACGTCTTATA
CGATGAGCAACATCAGTTAATAGCAGGTAGTCATGCTCAAACAGTCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTAT
ATAATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAGGGTATTTCATTTAGTGAGGTTACAATTGTTGCCAAA
GAAATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGACATTACGTTACTCGTTTCTTCAAGAACAAGAAATGA
TATCATTTCTCATACATTCAATCAATATGGTATTCCTATAGTAACAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTG
AAGTGATGGTTATGTTAGATACATTACGCACCATTAATAACCCAAGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCA
CCGATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACTTCAAAAAGACAATGAGCTAGATAAAGATTGCCTATA
TGACAAGATACAAAGGGCTGTGATTGGAAGAGGTGCTCATCCTGAATTGATTCACGATACCTTGCTTGGCAAGTTAAATG
TTTTTTTAAAGACGTTGAAAAGCTGGCGTCGATACGCTAAGCTAGGGTCGTTGTATGACTTGATTTGGAAAATTTTTAAT
GATCGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGAACAAGCACAAGCTAATCTATACGCATTAGCTCTACG
TGCTAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTTTTATTAAAATGATTGATAAGGTACTTGAGACGCAAA
ATGACTTAGCTGATGTGGAAGTGGCTACTCCTAAACAAGCTGTTAATTTAATGACCATTCACAAGTCTAAAGGTTTACAA
TTTCCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAATGACAGATATTCATAAATCATTTATTCTGAATCGGCA
GCACGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTACTTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCA
TGGAAACCTTACCTTATCAATTGAACAAACAAGAGTTGCGCTTAGCAACTTTATCAGAAGAAATGCGCTTACTGTATGTT
GCTATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGCTAGTAAGAGCAAAAGTCAAGAAATCACAGATCCTAA
AAAGTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTATTGACATTCCAAGATTGGCTATTAGCAATAGCAGATA
TATTTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAAGATAGTGATTTGACACAAGAGTCAGTCGGACGACTT
CAAACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCGTCAATCAGAAACAATTGCACGGGCTTTAGATATGTT
AGAAGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTCATTTGCCAACAGTTCGAACGCCTAGCCAACTTAAGG
CAACTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATAGAGAAATCTTCTCGATCGCTATCTGATTTTACTTTG
CCACATTTTTCAAAAAAAGCAAAAGTTGAAGCAAGTCATATTGGATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTT
GTCAAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAGGAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTG
ATCTCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGCCAATTTTTTCAGACTTACCAAAAACACTTGTATCGA
GAAGCGCCATTTGCTATTTTAAAACTTGACCCTATCAGTCAAGAAGAGTATGTCCTACGTGGTATTATAGATGCCTACTT
TTTGTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATAAATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACC
AACAACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTATAAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATG
GGAGGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(30-464)

UvrD-like helicase C-terminal domain (UvrD_C)

(474-892)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1046-1197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

48.284

100

0.488