Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   RMP66_RS06450 Genome accession   NZ_CP135094
Coordinates   1300905..1302131 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain 1547095     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1295905..1307131
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP66_RS06420 (RMP66_06420) - 1295938..1296162 (-) 225 WP_002934981.1 hypothetical protein -
  RMP66_RS06425 (RMP66_06425) - 1296224..1297531 (-) 1308 WP_002934980.1 excalibur calcium-binding domain-containing protein -
  RMP66_RS06430 (RMP66_06430) - 1297666..1297848 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  RMP66_RS06435 (RMP66_06435) lepA 1297898..1299730 (-) 1833 WP_002943192.1 translation elongation factor 4 -
  RMP66_RS06440 (RMP66_06440) ndk 1299826..1300239 (-) 414 WP_024394314.1 nucleoside-diphosphate kinase -
  RMP66_RS06445 (RMP66_06445) yihA 1300262..1300849 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  RMP66_RS06450 (RMP66_06450) clpX 1300905..1302131 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  RMP66_RS06455 (RMP66_06455) - 1302329..1302841 (-) 513 WP_024394316.1 dihydrofolate reductase -
  RMP66_RS06460 (RMP66_06460) - 1303017..1303856 (-) 840 WP_024394317.1 thymidylate synthase -
  RMP66_RS06465 (RMP66_06465) - 1303909..1304211 (-) 303 WP_024394318.1 hypothetical protein -
  RMP66_RS06470 (RMP66_06470) - 1304223..1304501 (-) 279 WP_024394319.1 hypothetical protein -
  RMP66_RS06475 (RMP66_06475) - 1304627..1305586 (-) 960 WP_024394320.1 ROK family glucokinase -
  RMP66_RS06480 (RMP66_06480) - 1305682..1306017 (-) 336 WP_024394321.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=885095 RMP66_RS06450 WP_002934974.1 1300905..1302131(-) (clpX) [Streptococcus suis strain 1547095]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=885095 RMP66_RS06450 WP_002934974.1 1300905..1302131(-) (clpX) [Streptococcus suis strain 1547095]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACTGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGATACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAGGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574