Detailed information NTG0885079

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: RMP66_RS02275
• Genome accession: NZ_CP135094
• Coordinates: 454369..456606 (+)
• Length: 745 a.a.
• NCBI ID: WP_043033064.1
• Uniprot ID: -
• Organism: Streptococcus suis strain 1547095
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 449369..461606

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RMP66_RS02250 (RMP66_02250)	-	449438..450367 (-)	930	WP_009909659.1	ABC transporter substrate-binding protein	-
RMP66_RS02255 (RMP66_02255)	-	450364..451164 (-)	801	WP_013730319.1	ABC transporter ATP-binding protein	-
RMP66_RS02260 (RMP66_02260)	-	451316..452761 (-)	1446	WP_013730320.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
RMP66_RS02265 (RMP66_02265)	-	452907..453653 (+)	747	WP_014735985.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
RMP66_RS02270 (RMP66_02270)	comEA/celA/cilE	453723..454385 (+)	663	WP_079394055.1	helix-hairpin-helix domain-containing protein	Machinery gene
RMP66_RS02275 (RMP66_02275)	comEC/celB	454369..456606 (+)	2238	WP_043033064.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
RMP66_RS02280 (RMP66_02280)	-	456608..456751 (+)	144	WP_002935351.1	transposase	-
RMP66_RS02285 (RMP66_02285)	-	456930..457586 (+)	657	WP_002935353.1	CBS domain-containing protein	-
RMP66_RS02290 (RMP66_02290)	-	457680..458507 (+)	828	WP_002935354.1	hypothetical protein	-
RMP66_RS02295 (RMP66_02295)	-	458513..459784 (+)	1272	WP_002935355.1	toxic anion resistance protein	-
RMP66_RS02300 (RMP66_02300)	-	459821..460687 (-)	867	WP_002935357.1	YitT family protein	-
RMP66_RS02305 (RMP66_02305)	tmk	460862..461500 (+)	639	WP_002935358.1	dTMP kinase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84157.32 Da
• Isoelectric Point: 8.1369

>NTDB_id=885079 RMP66_RS02275 WP_043033064.1 454369..456606(+) (comEC/celB) [Streptococcus suis strain 1547095]
MLRSIKLPCQPIHLALLAVAAYFVVRSFSLLTMGLLSLVLAVFGVRQGKAVFLRTLPLLALCGLFFGFQKLQWNRADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQTYFQELADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKITVIKKIVPVQSRNVFDWLSSWRRQALVYIKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCFLLL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMIYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPIIKITWVNGFFVLMEKIIVWVADLGLRPWILGKPSVVILILLLVCLFLLYDFHRKKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFMRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVHIGRIYVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
KTNFLFTGDLEQGELDLIESYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=885079 RMP66_RS02275 WP_043033064.1 454369..456606(+) (comEC/celB) [Streptococcus suis strain 1547095]
ATGTTACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCTCTTTTGGCGGTGGCAGCCTACTTTGTAGTCCGCTC
TTTTTCCCTCTTGACAATGGGCCTGCTCAGTTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGGCAGTTTTCCTCA
GAACGCTGCCGCTTCTAGCCCTGTGTGGTCTCTTTTTCGGATTTCAAAAGCTTCAATGGAATCGAGCAGACCAGTCAGCC
CCAGAGCAAGTCACAACTGTTCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGTCTGTCCTTTCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAGAGCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGAGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCAAGATTACGGTAATCAAGAAGATTGTCCCTGTCCAGTCTAGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCAGCTCCTATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTGGGCTTGCGGAAGCTGGATAACTTTGCGGTGACAGTTTTTGTCTGTTTCTTGTTGCTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTGATGATCTATTTCTTTG
CCTTCCAGCCCCTGTCTATTCTCTTGACTTTTGTATTTTCCTTTGTCTTTGATGTCCTGCTCTTGCCAGGCTTGTCGGTC
ATTTTTCTCTTATCACCAATTATCAAGATTACCTGGGTCAACGGATTTTTCGTCTTGATGGAAAAAATTATTGTCTGGGT
GGCAGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGTGGTAATTCTTATTCTCTTGCTGGTCTGTCTCTTCT
TACTTTATGATTTCCACAGAAAAAAGAAATGGCTCTTAGGACTGAGCCTGGTCCTTGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGTGACAGCATCTTTATGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTTCTGACACACACCGACACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTCCATATTGGTCGAATTTACGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATTAATGTGCCTGTCCATGTGGTCAAAGTGGGCGACCGCTTGCCGATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGAGACGGTGGCAATAATGACTCCATTGTCCTTTATGGTCGCTTGCTG
AAAACTAATTTTCTCTTTACAGGGGACTTGGAGCAGGGGGAGTTGGACTTGATAGAATCTTATCCTAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGATAGTCGCAATATCCAA
GTCTATCGTACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-460)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Domain of unknown function (DUF4131) (DUF4131) (30-172)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.24	99.732	0.541
comEC/celB	Streptococcus mitis NCTC 12261	53.414	100	0.536
comEC/celB	Streptococcus pneumoniae TIGR4	52.463	100	0.529
comEC/celB	Streptococcus pneumoniae Rx1	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae D39	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae R6	52.197	100	0.526
comEC	Lactococcus lactis subsp. cremoris KW2	49.332	100	0.495