Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   RMP65_RS02575 Genome accession   NZ_CP135089
Coordinates   490192..492420 (-) Length   742 a.a.
NCBI ID   WP_015646546.1    Uniprot ID   A0A0M9FFN0
Organism   Streptococcus suis strain ID34567     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 485192..497420
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP65_RS02555 (RMP65_02555) - 485755..486198 (+) 444 WP_313680653.1 GNAT family N-acetyltransferase -
  RMP65_RS02560 (RMP65_02560) ileS 486209..488998 (+) 2790 WP_313680654.1 isoleucine--tRNA ligase -
  RMP65_RS02565 (RMP65_02565) - 489182..489490 (-) 309 WP_002938710.1 DUF1827 family protein -
  RMP65_RS02570 (RMP65_02570) - 489545..490006 (-) 462 WP_002938708.1 NUDIX hydrolase -
  RMP65_RS02575 (RMP65_02575) clpE 490192..492420 (-) 2229 WP_015646546.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  RMP65_RS02580 (RMP65_02580) - 492644..492874 (+) 231 WP_002938704.1 DUF1797 family protein -
  RMP65_RS02585 (RMP65_02585) - 493000..493689 (+) 690 WP_002938702.1 amino acid ABC transporter permease -
  RMP65_RS02590 (RMP65_02590) - 493682..494416 (+) 735 WP_024401973.1 amino acid ABC transporter ATP-binding protein -
  RMP65_RS02595 (RMP65_02595) - 494650..495498 (+) 849 WP_044685945.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 82596.95 Da        Isoelectric Point: 5.2782

>NTDB_id=884924 RMP65_RS02575 WP_015646546.1 490192..492420(-) (clpE) [Streptococcus suis strain ID34567]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=884924 RMP65_RS02575 WP_015646546.1 490192..492420(-) (clpE) [Streptococcus suis strain ID34567]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATTATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATCCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAGGAAATCGAAGCCATCGTAGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCAGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTCGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGTCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATACCATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGT
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(476-639)

AAA lid domain (AAA_lid_9)

(291-389)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(647-721)

ATPase family associated with various cellular activities (AAA) (AAA)

(153-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FFN0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.361

100

0.837
  clpE Streptococcus pneumoniae D39

82.361

100

0.837
  clpE Streptococcus pneumoniae R6

82.361

100

0.837
  clpE Streptococcus pneumoniae TIGR4

82.361

100

0.837
  clpE Streptococcus mutans UA159

82.377

100

0.832
  clpC Lactococcus lactis subsp. cremoris KW2

77.655

97.709

0.759
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

87.601

0.46
  clpC Streptococcus mutans UA159

48.558

84.097

0.408
  clpC Streptococcus thermophilus LMD-9

48.248

84.636

0.408
  clpC Streptococcus thermophilus LMG 18311

47.93

84.636

0.406
  clpC Streptococcus pneumoniae TIGR4

47.84

84.232

0.403
  clpC Streptococcus pneumoniae Rx1

47.84

84.232

0.403
  clpC Streptococcus pneumoniae D39

47.84

84.232

0.403
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.815

84.636

0.396