Detailed information NTG0884559

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: Q9J89_RS09925
• Genome accession: NZ_CP135051
• Coordinates: 2055984..2057027 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain TWSL_1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2050984..2062027

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q9J89_RS09900	-	2052040..2052765 (+)	726	WP_023373124.1	type 1 glutamine amidotransferase	-
Q9J89_RS09905	-	2052833..2053819 (-)	987	WP_015364857.1	aromatic acid exporter family protein	-
Q9J89_RS09910	map	2053986..2054741 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
Q9J89_RS09915	-	2054885..2055271 (+)	387	WP_002466133.1	DUF2543 family protein	-
Q9J89_RS09920	liaF	2055286..2055987 (+)	702	WP_015364858.1	cell wall-active antibiotics response protein LiaF	-
Q9J89_RS09925	vraS	2055984..2057027 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
Q9J89_RS09930	vraR	2057017..2057646 (+)	630	WP_058710065.1	response regulator transcription factor	Regulator
Q9J89_RS09935	-	2057705..2058940 (-)	1236	WP_015364859.1	YihY/virulence factor BrkB family protein	-
Q9J89_RS09940	-	2059170..2059454 (-)	285	WP_002466132.1	YtxH domain-containing protein	-
Q9J89_RS09945	-	2059461..2059925 (-)	465	WP_145541523.1	low molecular weight protein-tyrosine-phosphatase	-
Q9J89_RS09950	-	2060072..2060275 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
Q9J89_RS09955	-	2060288..2061529 (+)	1242	WP_058710066.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=884559 Q9J89_RS09925 WP_002466111.1 2055984..2057027(+) (vraS) [Staphylococcus warneri strain TWSL_1]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=884559 Q9J89_RS09925 WP_002466111.1 2055984..2057027(+) (vraS) [Staphylococcus warneri strain TWSL_1]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTTCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGCAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948