Detailed information NTG0884030

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: M9H31_RS04605
• Genome accession: NZ_CP134839
• Coordinates: 978921..979967 (+)
• Length: 348 a.a.
• NCBI ID: WP_002447441.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain ADQBK
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 973921..984967

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H31_RS04580 (M9H31_04580)	isaB	975061..975597 (+)	537	WP_002447446.1	immunodominant staphylococcal antigen IsaB family protein	-
M9H31_RS04585 (M9H31_04585)	-	975749..976735 (-)	987	WP_002447445.1	FUSC family protein	-
M9H31_RS04590 (M9H31_04590)	map	976909..977664 (+)	756	WP_002447444.1	type I methionyl aminopeptidase	-
M9H31_RS04595 (M9H31_04595)	-	977822..978208 (+)	387	WP_002495657.1	hypothetical protein	-
M9H31_RS04600 (M9H31_04600)	liaF	978223..978924 (+)	702	WP_002447442.1	cell wall-active antibiotics response protein LiaF	-
M9H31_RS04605 (M9H31_04605)	vraS	978921..979967 (+)	1047	WP_002447441.1	sensor histidine kinase	Regulator
M9H31_RS04610 (M9H31_04610)	vraR	979957..980586 (+)	630	WP_002447440.1	two-component system response regulator VraR	Regulator
M9H31_RS04615 (M9H31_04615)	-	980643..981821 (-)	1179	WP_002447439.1	YihY/virulence factor BrkB family protein	-
M9H31_RS04620 (M9H31_04620)	-	982227..982511 (-)	285	WP_002447438.1	YtxH domain-containing protein	-
M9H31_RS04625 (M9H31_04625)	-	982519..982983 (-)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
M9H31_RS04630 (M9H31_04630)	-	983125..983340 (+)	216	WP_001830421.1	DUF1128 domain-containing protein	-
M9H31_RS04635 (M9H31_04635)	-	983342..984583 (+)	1242	WP_002447437.1	aminopeptidase	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40114.53 Da
• Isoelectric Point: 5.8512

>NTDB_id=884030 M9H31_RS04605 WP_002447441.1 978921..979967(+) (vraS) [Staphylococcus epidermidis strain ADQBK]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNLLIVFLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVLHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=884030 M9H31_RS04605 WP_002447441.1 978921..979967(+) (vraS) [Staphylococcus epidermidis strain ADQBK]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAATATTATCTTTTTTCAAGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATAGTTTTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCC
CAAATAGAAAGATCAATAGAAGGACAAACAGTGGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAGAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAGCGACTTGCTAGGGAATTGCATGATTCTGTTAGC
CAACAATTATTTGCTGCGAGCATGATGCTATCAGCAATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTGTTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTCTAGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTTTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGTATTGAAGATCATTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACGAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTAAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACAAGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.442	98.851	0.914