Detailed information NTG0883827

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RNT94_RS07115
• Genome accession: NZ_CP134803
• Coordinates: 1447976..1449019 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SA85_2
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1442976..1454019

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RNT94_RS07085	-	1443397..1444653 (-)	1257	WP_001793428.1	aminopeptidase	-
RNT94_RS07090	-	1444656..1444856 (-)	201	WP_000180460.1	DUF1128 family protein	-
RNT94_RS07095	-	1445003..1445467 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RNT94_RS07100	-	1445474..1445749 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RNT94_RS07105	-	1446027..1447244 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
RNT94_RS07110	vraR	1447357..1447986 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RNT94_RS07115	vraS	1447976..1449019 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RNT94_RS07120	liaF	1449016..1449717 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RNT94_RS07125	-	1449732..1450118 (-)	387	WP_001110182.1	hypothetical protein	-
RNT94_RS07130	map	1450335..1451093 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
RNT94_RS07135	-	1451677..1452663 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
RNT94_RS07140	-	1452852..1453265 (-)	414	WP_025174370.1	hypothetical protein	-
RNT94_RS07145	-	1453294..1453404 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=883827 RNT94_RS07115 WP_001017131.1 1447976..1449019(-) (vraS) [Staphylococcus aureus strain SA85_2]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=883827 RNT94_RS07115 WP_001017131.1 1447976..1449019(-) (vraS) [Staphylococcus aureus strain SA85_2]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1