Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   RNU01_RS03525 Genome accession   NZ_CP134801
Coordinates   706590..707306 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain SA73_2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 701590..712306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RNU01_RS03505 - 702682..703632 (+) 951 WP_029625646.1 LacI family DNA-binding transcriptional regulator -
  RNU01_RS03510 - 703781..705265 (+) 1485 WP_000141435.1 sucrose-6-phosphate hydrolase -
  RNU01_RS03515 - 705262..706221 (+) 960 WP_001253302.1 carbohydrate kinase -
  RNU01_RS03520 - 706409..706518 (-) 110 Protein_688 hypothetical protein -
  RNU01_RS03525 agrA 706590..707306 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  RNU01_RS03530 agrC 707325..708617 (-) 1293 WP_001657119.1 quorum-sensing sensor histidine kinase AgrC -
  RNU01_RS03535 agrD 708642..708782 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  RNU01_RS03540 agrB 708779..709348 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  RNU01_RS03545 hld 709638..709718 (+) 81 WP_000046022.1 delta-hemolysin -
  RNU01_RS03550 - 710318..711103 (-) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  RNU01_RS03555 - 711464..712090 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=883758 RNU01_RS03525 WP_000688498.1 706590..707306(-) (agrA) [Staphylococcus aureus strain SA73_2]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=883758 RNU01_RS03525 WP_000688498.1 706590..707306(-) (agrA) [Staphylococcus aureus strain SA73_2]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996