Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   QN337_RS01370 Genome accession   NZ_CP134688
Coordinates   250549..252810 (-) Length   753 a.a.
NCBI ID   WP_000882544.1    Uniprot ID   X5KCK2
Organism   Streptococcus agalactiae strain MA07     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 245549..257810
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QN337_RS01350 (QN337_01340) - 245625..246395 (+) 771 WP_001131467.1 DivIVA domain-containing protein -
  QN337_RS01355 (QN337_01345) ileS 246680..249472 (+) 2793 WP_000768156.1 isoleucine--tRNA ligase -
  QN337_RS01360 (QN337_01350) - 249542..249844 (-) 303 WP_001237037.1 DUF1827 family protein -
  QN337_RS01365 (QN337_01355) - 249908..250363 (-) 456 WP_000184290.1 NUDIX hydrolase -
  QN337_RS01370 (QN337_01360) clpE 250549..252810 (-) 2262 WP_000882544.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  QN337_RS01375 (QN337_01365) - 253108..253338 (+) 231 WP_000443582.1 DUF1797 family protein -
  QN337_RS01380 (QN337_01370) - 253479..254171 (+) 693 WP_001011647.1 amino acid ABC transporter permease -
  QN337_RS01385 (QN337_01375) - 254164..254898 (+) 735 WP_000230129.1 amino acid ABC transporter ATP-binding protein -
  QN337_RS01390 (QN337_01380) - 255185..256879 (+) 1695 WP_001106849.1 phospho-sugar mutase -

Sequence

Protein


Download         Length: 753 a.a.        Molecular weight: 83774.98 Da        Isoelectric Point: 5.2771

>NTDB_id=882739 QN337_RS01370 WP_000882544.1 250549..252810(-) (clpE) [Streptococcus agalactiae strain MA07]
MLCQNCKLNESTIHLYTNVNGKQKQVDLCQNCYQIIKTDPNNPLFSGLNHVSHAPGGINPFFDDFFGDLNNFRAFNGQDL
PNTPPTQAGGNRGGGNGNGRNNNRNQTATPPQAKGILEEFGINVTEIARHGDIDPVIGRDSEIIRVIEILNRRTKNNPVL
IGEPGVGKTAVVEGLAQKIVDGNVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVG
AGTAGEGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQKKYEDYHHVKY
NNDAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIEAENLKAQATREEDYERAAYFRDQIAK
YKEMQQQKVDDQDTPIITEKTIEHIIEEKTNIPVGDLKEKEQSQLINLADDLKQHVIGQDDAVIKIAKAIRRNRVGLGSP
NRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLI
LLDEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGSGKTEASVGFGASREGRTNSVLGQLGNFFSPEF
MNRFDGIIEFKALDKENLLNIVDIMLSDVNARLAINGIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDYY
LENPSEKELRAIMTSNGNIIIKSSKKTEESTKG

Nucleotide


Download         Length: 2262 bp        

>NTDB_id=882739 QN337_RS01370 WP_000882544.1 250549..252810(-) (clpE) [Streptococcus agalactiae strain MA07]
ATGCTCTGTCAAAACTGCAAACTAAACGAATCAACTATTCATTTGTATACAAATGTTAATGGAAAACAAAAGCAAGTTGA
TCTTTGTCAAAATTGCTACCAAATTATTAAAACTGACCCTAATAATCCACTTTTTTCAGGTTTAAATCATGTTTCACATG
CGCCTGGTGGCATCAATCCTTTCTTTGATGATTTCTTTGGAGATTTAAATAATTTCAGAGCCTTTAATGGCCAAGATTTA
CCAAACACTCCTCCTACACAAGCAGGAGGAAACCGAGGTGGAGGAAACGGTAATGGACGAAATAATAATCGCAACCAAAC
TGCAACTCCTCCTCAAGCCAAAGGGATTCTAGAAGAATTTGGTATCAATGTCACTGAAATAGCCCGCCATGGTGATATTG
ACCCTGTTATTGGACGTGACTCAGAAATTATTCGTGTTATCGAAATCCTTAATCGTCGTACAAAAAATAATCCTGTACTT
ATTGGCGAACCCGGCGTAGGGAAAACTGCCGTTGTTGAAGGACTTGCTCAGAAAATTGTTGATGGTAATGTGCCTCATAA
ACTTCAAGGCAAACAAGTTATTCGTTTGGATGTTGTGAGTCTAGTACAAGGAACGGGCATTCGTGGTCAATTTGAAGAAC
GCATGCAAAAGTTGATGGAAGAAATTCGTCAACGTCAAGATGTTATTCTATTCATAGATGAAATTCACGAAATAGTTGGA
GCTGGTACAGCTGGCGAAGGTAGTATGGATGCAGGTAATATTTTAAAACCTGCCCTTGCACGTGGAGAATTACAACTAGT
AGGTGCCACTACTCTCAATGAATATCGTATTATCGAAAAGGACGCTGCCTTAGAACGCCGTATGCAACCTGTAAAAGTCG
ATGAACCTTCTGTTGAAGAAACCATTACTATTTTGAAAGGTATCCAAAAAAAATACGAAGATTATCATCACGTAAAATAT
AATAATGATGCCATAGAAGCAGCTGCAGTACTATCTAATCGTTATATCCAAGACCGCTTTTTACCTGATAAAGCAATAGA
CTTATTAGATGAAGCTGGTTCTAAAATGAACCTAACACTAAATTTTGTTGATCCAAAAGAAATTGATCAACGTCTCATTG
AAGCAGAAAATTTAAAAGCGCAAGCGACTCGTGAAGAAGATTACGAACGTGCAGCTTACTTCCGTGACCAGATTGCAAAA
TATAAAGAAATGCAGCAACAAAAGGTCGACGATCAAGATACACCTATTATTACCGAAAAAACAATTGAGCACATCATTGA
AGAAAAAACGAATATCCCTGTTGGTGATTTAAAAGAAAAAGAACAATCTCAATTAATTAATCTCGCAGATGACTTGAAAC
AGCATGTGATCGGCCAGGATGACGCTGTCATTAAGATTGCAAAAGCTATTCGTCGTAATCGAGTTGGTCTTGGTAGCCCA
AACCGTCCTATTGGTTCCTTTTTATTTGTAGGACCAACCGGTGTTGGTAAAACTGAACTTTCTAAACAACTAGCAATTGA
GCTCTTTGGTTCAGCTGATAGTATGATTCGTTTTGATATGTCAGAGTACATGGAAAAGCATGCTGTTGCTAAATTAGTCG
GAGCGCCTCCAGGATACGTGGGATACGAGGAAGCTGGACAACTAACTGAAAAGGTTCGTCGAAATCCTTACTCGCTCATC
CTTCTAGATGAAATTGAAAAAGCTCATCCCGATGTCATGCATATGTTCTTGCAGGTCCTTGATGACGGTCGATTAACAGA
TGGACAAGGAAGAACTGTTAGTTTTAAAGATACCATTATCATCATGACCTCAAATGCTGGTTCTGGTAAAACTGAAGCAA
GTGTTGGCTTTGGTGCCTCACGAGAAGGTAGGACGAATTCCGTACTAGGTCAACTAGGTAACTTCTTCAGCCCTGAATTT
ATGAACCGCTTTGACGGTATTATTGAATTCAAGGCTTTAGATAAAGAGAATCTCCTCAATATCGTTGATATTATGTTATC
TGACGTTAATGCACGTCTCGCCATCAATGGTATTCATCTAGATGTCACTGATAAAGTGAAAGAAAAATTGGTTGATTTAG
GTTACGATCCCAAAATGGGAGCACGTCCATTACGTCGTACCATTCAAGAACATATTGAAGATGCTATCACAGATTACTAT
CTTGAGAATCCAAGCGAAAAAGAACTTCGTGCTATTATGACTAGCAATGGAAATATCATAATAAAATCTTCTAAAAAAAC
TGAGGAAAGTACAAAAGGTTGA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(159-276)

AAA lid domain (AAA_lid_9)

(297-394)

AAA domain (Cdc48 subfamily) (AAA_2)

(482-645)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(653-727)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB X5KCK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.809

100

0.859
  clpE Streptococcus pneumoniae Rx1

85.447

99.469

0.85
  clpE Streptococcus pneumoniae D39

85.447

99.469

0.85
  clpE Streptococcus pneumoniae R6

85.447

99.469

0.85
  clpE Streptococcus pneumoniae TIGR4

85.314

99.469

0.849
  clpC Lactococcus lactis subsp. cremoris KW2

74.867

99.867

0.748
  clpC Bacillus subtilis subsp. subtilis str. 168

51.18

90.04

0.461
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.528

83.267

0.396
  clpC Streptococcus pneumoniae Rx1

47.003

84.197

0.396
  clpC Streptococcus pneumoniae D39

47.003

84.197

0.396
  clpC Streptococcus pneumoniae TIGR4

46.845

84.197

0.394
  clpC Streptococcus mutans UA159

47.03

82.736

0.389
  clpC Streptococcus thermophilus LMD-9

46.276

83.798

0.388
  clpC Streptococcus thermophilus LMG 18311

45.959

83.798

0.385