Detailed information NTG0880803

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RKV28_RS10550
• Genome accession: NZ_CP134534
• Coordinates: 2094092..2095135 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain KNIH_5618
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2089092..2100135

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RKV28_RS10520	-	2089513..2090769 (-)	1257	WP_001795108.1	aminopeptidase	-
RKV28_RS10525	-	2090772..2090972 (-)	201	WP_000180460.1	DUF1128 family protein	-
RKV28_RS10530	-	2091119..2091583 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
RKV28_RS10535	-	2091590..2091865 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
RKV28_RS10540	-	2092143..2093360 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
RKV28_RS10545	vraR	2093473..2094102 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RKV28_RS10550	vraS	2094092..2095135 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RKV28_RS10555	liaF	2095132..2095833 (-)	702	WP_233231723.1	cell wall-active antibiotics response protein LiaF	-
RKV28_RS10560	-	2095848..2096234 (-)	387	WP_001110179.1	hypothetical protein	-
RKV28_RS10565	map	2096451..2097209 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
RKV28_RS10570	-	2097740..2098726 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
RKV28_RS10575	-	2099157..2099570 (-)	414	WP_001557448.1	hypothetical protein	-
RKV28_RS10580	-	2099599..2099709 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=880803 RKV28_RS10550 WP_001017131.1 2094092..2095135(-) (vraS) [Staphylococcus aureus strain KNIH_5618]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=880803 RKV28_RS10550 WP_001017131.1 2094092..2095135(-) (vraS) [Staphylococcus aureus strain KNIH_5618]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1