Detailed information NTG0880715

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: RKV26_RS09900
• Genome accession: NZ_CP134532
• Coordinates: 1996028..1997071 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain KNIH_6268
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1991028..2002071

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RKV26_RS09870	-	1991446..1992702 (-)	1257	WP_001793428.1	aminopeptidase	-
RKV26_RS09875	-	1992705..1992905 (-)	201	WP_000180460.1	DUF1128 family protein	-
RKV26_RS09880	-	1993052..1993516 (+)	465	WP_154284135.1	low molecular weight protein-tyrosine-phosphatase	-
RKV26_RS09885	-	1993523..1993798 (+)	276	WP_154284136.1	YtxH domain-containing protein	-
RKV26_RS09890	-	1994076..1995293 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
RKV26_RS09895	vraR	1995409..1996038 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
RKV26_RS09900	vraS	1996028..1997071 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
RKV26_RS09905	liaF	1997068..1997769 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
RKV26_RS09910	-	1997784..1998170 (-)	387	WP_001110179.1	hypothetical protein	-
RKV26_RS09915	map	1998387..1999145 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
RKV26_RS09920	-	1999668..2000654 (+)	987	WP_154284137.1	aromatic acid exporter family protein	-
RKV26_RS09925	-	2001085..2001498 (-)	414	WP_154284138.1	hypothetical protein	-
RKV26_RS09930	-	2001527..2001637 (-)	111	WP_154284139.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=880715 RKV26_RS09900 WP_001017131.1 1996028..1997071(-) (vraS) [Staphylococcus aureus strain KNIH_6268]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=880715 RKV26_RS09900 WP_001017131.1 1996028..1997071(-) (vraS) [Staphylococcus aureus strain KNIH_6268]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTTTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTACGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1