Detailed information NTG0880344

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: RJW53_RS10280
• Genome accession: NZ_CP134488
• Coordinates: 2061983..2064436 (-)
• Length: 817 a.a.
• NCBI ID: WP_074392671.1
• Uniprot ID: -
• Organism: Streptococcus suis strain NLS50
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2056983..2069436

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RJW53_RS10250 (RJW53_10250)	hslO	2058109..2058975 (+)	867	WP_074392670.1	Hsp33 family molecular chaperone HslO	-
RJW53_RS10255 (RJW53_10255)	dusB	2058968..2059951 (+)	984	WP_074389071.1	tRNA dihydrouridine synthase DusB	-
RJW53_RS10260 (RJW53_10260)	-	2060300..2060542 (-)	243	WP_024388245.1	hypothetical protein	-
RJW53_RS10265 (RJW53_10265)	-	2060539..2060772 (-)	234	WP_024388244.1	hypothetical protein	-
RJW53_RS10270 (RJW53_10270)	-	2060792..2061175 (-)	384	WP_024416526.1	hypothetical protein	-
RJW53_RS10275 (RJW53_10275)	-	2061364..2061864 (-)	501	WP_074389072.1	adenylyltransferase/cytidyltransferase family protein	-
RJW53_RS10280 (RJW53_10280)	clpC	2061983..2064436 (-)	2454	WP_074392671.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
RJW53_RS10285 (RJW53_10285)	-	2064440..2064898 (-)	459	WP_311047930.1	CtsR family transcriptional regulator	-
RJW53_RS10290 (RJW53_10290)	-	2065168..2065506 (+)	339	WP_074389074.1	thioredoxin domain-containing protein	-
RJW53_RS10295 (RJW53_10295)	-	2065506..2066132 (+)	627	WP_074389075.1	GNAT family acetyltransferase	-
RJW53_RS10300 (RJW53_10300)	tsf	2066682..2067722 (-)	1041	WP_029943831.1	translation elongation factor Ts	-
RJW53_RS10305 (RJW53_10305)	rpsB	2067876..2068652 (-)	777	WP_024381114.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90460.99 Da
• Isoelectric Point: 6.2908

>NTDB_id=880344 RJW53_RS10280 WP_074392671.1 2061983..2064436(-) (clpC) [Streptococcus suis strain NLS50]
MKISTGLQRVFEDSQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFCFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKKLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLAVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLTTGST
LKVGVNGEELKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=880344 RJW53_RS10280 WP_074392671.1 2061983..2064436(-) (clpC) [Streptococcus suis strain NLS50]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATTCCCAGTTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCCGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACGGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGTTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTGTTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACCAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTCATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ATGACATCGAGGAAGATGGTCAGGTCATCCTCTTCATCGATGAGTTGCATACCATTATGGGTTCTGGTTCAGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACAACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGATGCAGCCTTGGTCCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACTGGTTTAAAAGGTACTTTTGAAAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAAGCTGCCAGATTCAGCCATTGATTTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGATTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTTTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCAGTTAGCAGAGCTATTC
GTCGTAATCAGTCAGGGATTCGTACAGGTCGTAGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTCGCAGCCAGCCGTCTCAATGGAGCGCCTCCAGGCTACGTGGGCTATGAAGAAGGTGGCGAATTGACGGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTTAACGTGCTTTTG
CAGGTCTTGGATGATGGTGTTCTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACCATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGGGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGTTGGCTGTAACAGCTGAGAAAGG
AATTACTCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAACAAGGTTATGACCCAGAAATGGGAGCTCGTCCGC
TACGTAGGCTCTTACAAACCAAATTGGAAGATCCGTTGGCAGAAATGTTACTCCGTGGTGACTTGACTACTGGTTCGACC
TTGAAGGTTGGAGTCAATGGTGAAGAGCTCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-129)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-56)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

• AAA lid domain (AAA_lid_9) (372-457)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	71.656	99.755	0.715
clpC	Streptococcus pneumoniae Rx1	71.656	99.755	0.715
clpC	Streptococcus pneumoniae D39	71.656	99.755	0.715
clpC	Streptococcus mutans UA159	66.462	99.633	0.662
clpC	Streptococcus thermophilus LMD-9	63.723	100	0.654
clpC	Streptococcus thermophilus LMG 18311	64.14	100	0.652
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.222	100	0.503
clpC	Bacillus subtilis subsp. subtilis str. 168	43.373	100	0.441