Detailed information NTG0880227

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: RJW49_RS07880
• Genome accession: NZ_CP134477
• Coordinates: 1547908..1548957 (-)
• Length: 349 a.a.
• NCBI ID: WP_014736227.1
• Uniprot ID: A0A0Z8PJI1
• Organism: Streptococcus suis strain NLS40
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1542908..1553957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RJW49_RS07860 (RJW49_07860)	tnpA	1544009..1544522 (-)	514	Protein_1509	IS200/IS605 family transposase	-
RJW49_RS07865 (RJW49_07865)	-	1545434..1545961 (-)	528	WP_002942846.1	VanZ family protein	-
RJW49_RS07870 (RJW49_07870)	rlmN	1545958..1547070 (-)	1113	WP_014736226.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
RJW49_RS07875 (RJW49_07875)	-	1547079..1547720 (-)	642	WP_014638483.1	YutD-like domain-containing protein	-
RJW49_RS07880 (RJW49_07880)	sepM	1547908..1548957 (-)	1050	WP_014736227.1	SepM family pheromone-processing serine protease	Regulator
RJW49_RS07885 (RJW49_07885)	coaD	1548944..1549432 (-)	489	WP_014736228.1	pantetheine-phosphate adenylyltransferase	-
RJW49_RS07890 (RJW49_07890)	rsmD	1549422..1549961 (-)	540	WP_014638485.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
RJW49_RS07895 (RJW49_07895)	-	1550270..1550992 (-)	723	WP_311048022.1	serine protease	-
RJW49_RS07900 (RJW49_07900)	-	1551049..1551435 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
RJW49_RS07905 (RJW49_07905)	-	1551435..1551653 (-)	219	WP_004194736.1	YqgQ family protein	-
RJW49_RS07910 (RJW49_07910)	-	1551950..1552552 (-)	603	WP_074393363.1	response regulator transcription factor	-
RJW49_RS07915 (RJW49_07915)	-	1552549..1553643 (-)	1095	WP_171840990.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37775.85 Da
• Isoelectric Point: 4.6112

>NTDB_id=880227 RJW49_RS07880 WP_014736227.1 1547908..1548957(-) (sepM) [Streptococcus suis strain NLS40]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLELGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=880227 RJW49_RS07880 WP_014736227.1 1547908..1548957(-) (sepM) [Streptococcus suis strain NLS40]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAACTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A0Z8PJI1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	61.095	99.427	0.607