Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   RJW49_RS07640 Genome accession   NZ_CP134477
Coordinates   1500492..1502720 (+) Length   742 a.a.
NCBI ID   WP_074393500.1    Uniprot ID   -
Organism   Streptococcus suis strain NLS40     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1495492..1507720
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW49_RS07615 (RJW49_07615) - 1495786..1496085 (-) 300 WP_014735557.1 hypothetical protein -
  RJW49_RS07620 (RJW49_07620) - 1497515..1498363 (-) 849 WP_014735556.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  RJW49_RS07625 (RJW49_07625) - 1498493..1499230 (-) 738 WP_014735555.1 amino acid ABC transporter ATP-binding protein -
  RJW49_RS07630 (RJW49_07630) - 1499223..1499912 (-) 690 WP_002938702.1 amino acid ABC transporter permease -
  RJW49_RS07635 (RJW49_07635) - 1500038..1500268 (-) 231 WP_014735554.1 DUF1797 family protein -
  RJW49_RS07640 (RJW49_07640) clpE 1500492..1502720 (+) 2229 WP_074393500.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  RJW49_RS07645 (RJW49_07645) - 1502906..1503367 (+) 462 WP_014735552.1 NUDIX hydrolase -
  RJW49_RS07650 (RJW49_07650) - 1503422..1503757 (+) 336 WP_013730208.1 DUF1827 family protein -
  RJW49_RS07655 (RJW49_07655) - 1504310..1505512 (+) 1203 WP_079759536.1 IS110 family transposase -
  RJW49_RS07660 (RJW49_07660) - 1505799..1506074 (-) 276 WP_002936247.1 HU family DNA-binding protein -
  RJW49_RS07665 (RJW49_07665) - 1506164..1506760 (-) 597 WP_012027570.1 YpmS family protein -
  RJW49_RS07670 (RJW49_07670) - 1506732..1507565 (-) 834 WP_014636487.1 SGNH/GDSL hydrolase family protein -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 82526.92 Da        Isoelectric Point: 5.2753

>NTDB_id=880225 RJW49_RS07640 WP_074393500.1 1500492..1502720(+) (clpE) [Streptococcus suis strain NLS40]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNCREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASNLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHLTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=880225 RJW49_RS07640 WP_074393500.1 1500492..1502720(+) (clpE) [Streptococcus suis strain NLS40]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACCCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGAGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATTGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGCTCTGCAGGCGAT
GGTAACATGGATGCAGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTGGTCGGTGCAACAACGCTCAA
CGAGTACCGTATTATCGAAAAAGATGCCGCCCTAGAACGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACTATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCTGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAAGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAGGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAAAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTAACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCCATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCTGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGGACAGT
CAGCTTCAAAGATGCCATTATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGC
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATTTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(153-272)

AAA domain (Cdc48 subfamily) (AAA_2)

(476-639)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(647-721)

AAA lid domain (AAA_lid_9)

(291-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.095

100

0.834
  clpE Streptococcus pneumoniae D39

82.095

100

0.834
  clpE Streptococcus pneumoniae R6

82.095

100

0.834
  clpE Streptococcus pneumoniae TIGR4

82.095

100

0.834
  clpE Streptococcus mutans UA159

81.842

100

0.826
  clpC Lactococcus lactis subsp. cremoris KW2

77.241

97.709

0.755
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

87.601

0.46
  clpC Streptococcus thermophilus LMD-9

48.089

84.636

0.407
  clpC Streptococcus mutans UA159

48.397

84.097

0.407
  clpC Streptococcus thermophilus LMG 18311

47.771

84.636

0.404
  clpC Streptococcus pneumoniae Rx1

47.84

84.232

0.403
  clpC Streptococcus pneumoniae D39

47.84

84.232

0.403
  clpC Streptococcus pneumoniae TIGR4

47.84

84.232

0.403
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.815

84.636

0.396