Detailed information NTG0880124

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: RJW56_RS08405
• Genome accession: NZ_CP134472
• Coordinates: 1689036..1690085 (-)
• Length: 349 a.a.
• NCBI ID: WP_009910567.1
• Uniprot ID: A0A7Y6RPS3
• Organism: Streptococcus suis strain 1522228
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1684036..1695085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RJW56_RS08385 (RJW56_08385)	nadE	1684864..1685688 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
RJW56_RS08390 (RJW56_08390)	-	1686562..1687089 (-)	528	WP_004194600.1	VanZ family protein	-
RJW56_RS08395 (RJW56_08395)	rlmN	1687086..1688198 (-)	1113	WP_172051237.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
RJW56_RS08400 (RJW56_08400)	-	1688207..1688848 (-)	642	WP_004194595.1	YutD-like domain-containing protein	-
RJW56_RS08405 (RJW56_08405)	sepM	1689036..1690085 (-)	1050	WP_009910567.1	SepM family pheromone-processing serine protease	Regulator
RJW56_RS08410 (RJW56_08410)	coaD	1690072..1690560 (-)	489	WP_002939048.1	pantetheine-phosphate adenylyltransferase	-
RJW56_RS08415 (RJW56_08415)	rsmD	1690550..1691089 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
RJW56_RS08420 (RJW56_08420)	-	1691388..1692110 (-)	723	WP_013730502.1	hypothetical protein	-
RJW56_RS08425 (RJW56_08425)	-	1692167..1692553 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
RJW56_RS08430 (RJW56_08430)	-	1692553..1692771 (-)	219	WP_004194736.1	YqgQ family protein	-
RJW56_RS08435 (RJW56_08435)	-	1693071..1693673 (-)	603	WP_004194738.1	response regulator transcription factor	-
RJW56_RS08440 (RJW56_08440)	-	1693670..1694764 (-)	1095	WP_024394990.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37733.77 Da
• Isoelectric Point: 4.6112

>NTDB_id=880124 RJW56_RS08405 WP_009910567.1 1689036..1690085(-) (sepM) [Streptococcus suis strain 1522228]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLVKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSVPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=880124 RJW56_RS08405 WP_009910567.1 1689036..1690085(-) (sepM) [Streptococcus suis strain 1522228]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGGTTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTATCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ACCATACAGAGGTTCAAAGTTCGGTTCCAATTGATTTCCAAACGGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGAATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTTATTTCGGCAGCTAAGTCAGGTGCAAGTATTTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACGAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A7Y6RPS3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.519	99.427	0.602