Detailed information NTG0087963

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OCX19_RS10100
• Genome accession: NZ_AP024734
• Coordinates: 2033128..2034171 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 59691
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2028128..2039171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OCX19_RS10070	-	2028556..2029812 (-)	1257	WP_001793428.1	aminopeptidase	-
OCX19_RS10075	-	2029815..2030015 (-)	201	WP_000180460.1	DUF1128 family protein	-
OCX19_RS10080	-	2030162..2030626 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OCX19_RS10085	-	2030633..2030908 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
OCX19_RS10090	-	2031186..2032397 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
OCX19_RS10095	vraR	2032509..2033138 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
OCX19_RS10100	vraS	2033128..2034171 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OCX19_RS10105	liaF	2034168..2034869 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OCX19_RS10110	-	2034884..2035270 (-)	387	WP_001110179.1	hypothetical protein	-
OCX19_RS10115	map	2035487..2036245 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OCX19_RS10120	-	2036776..2037762 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
OCX19_RS10125	-	2038252..2038665 (-)	414	WP_001837236.1	hypothetical protein	-
OCX19_RS10130	-	2038694..2038805 (-)	112	Protein_1961	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=87963 OCX19_RS10100 WP_001017131.1 2033128..2034171(-) (vraS) [Staphylococcus aureus strain 59691]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=87963 OCX19_RS10100 WP_001017131.1 2033128..2034171(-) (vraS) [Staphylococcus aureus strain 59691]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1