Detailed information NTG0087920

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OCX17_RS09715
• Genome accession: NZ_AP024732
• Coordinates: 1975012..1976055 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 59621
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1970012..1981055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OCX17_RS09685	-	1970440..1971696 (-)	1257	WP_001793428.1	aminopeptidase	-
OCX17_RS09690	-	1971699..1971899 (-)	201	WP_000180460.1	DUF1128 family protein	-
OCX17_RS09695	-	1972046..1972510 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OCX17_RS09700	-	1972517..1972792 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
OCX17_RS09705	-	1973070..1974281 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
OCX17_RS09710	vraR	1974393..1975022 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
OCX17_RS09715	vraS	1975012..1976055 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OCX17_RS09720	liaF	1976052..1976753 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OCX17_RS09725	-	1976768..1977154 (-)	387	WP_001110179.1	hypothetical protein	-
OCX17_RS09730	map	1977371..1978129 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OCX17_RS09735	-	1978660..1979646 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
OCX17_RS09740	-	1980195..1980608 (-)	414	WP_001837236.1	hypothetical protein	-
OCX17_RS09745	-	1980637..1980748 (-)	112	Protein_1886	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=87920 OCX17_RS09715 WP_001017131.1 1975012..1976055(-) (vraS) [Staphylococcus aureus strain 59621]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=87920 OCX17_RS09715 WP_001017131.1 1975012..1976055(-) (vraS) [Staphylococcus aureus strain 59621]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1