Detailed information NTG0878846

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: WOC67_RS08480
• Genome accession: NZ_CP150758
• Coordinates: 1695708..1696751 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: Q99SZ7
• Organism: Staphylococcus aureus strain TUM22182
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1690708..1701751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC67_RS08450 (WOC67_08465)	-	1691137..1691247 (+)	111	WP_001790257.1	hypothetical protein	-
WOC67_RS08455 (WOC67_08470)	-	1691276..1691689 (+)	414	WP_001549145.1	hypothetical protein	-
WOC67_RS08460 (WOC67_08475)	-	1692120..1693106 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
WOC67_RS08465 (WOC67_08480)	map	1693634..1694392 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
WOC67_RS08470 (WOC67_08485)	-	1694609..1694995 (+)	387	WP_001110179.1	hypothetical protein	-
WOC67_RS08475 (WOC67_08490)	liaF	1695010..1695711 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
WOC67_RS08480 (WOC67_08495)	vraS	1695708..1696751 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
WOC67_RS08485 (WOC67_08500)	vraR	1696741..1697370 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
WOC67_RS08490 (WOC67_08505)	-	1697486..1698703 (-)	1218	WP_000037069.1	YihY/virulence factor BrkB family protein	-
WOC67_RS08495 (WOC67_08510)	-	1698981..1699256 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
WOC67_RS08500 (WOC67_08515)	-	1699263..1699727 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
WOC67_RS08505 (WOC67_08520)	-	1699874..1700074 (+)	201	WP_000180461.1	DUF1128 family protein	-
WOC67_RS08510 (WOC67_08525)	-	1700077..1701333 (+)	1257	WP_108932452.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=878846 WOC67_RS08480 WP_001017131.1 1695708..1696751(+) (vraS) [Staphylococcus aureus strain TUM22182]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=878846 WOC67_RS08480 WP_001017131.1 1695708..1696751(+) (vraS) [Staphylococcus aureus strain TUM22182]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: Q99SZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1