Detailed information NTG0087878

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: OCX16_RS10000
• Genome accession: NZ_AP024730
• Coordinates: 2019204..2020247 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain 59574
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2014204..2025247

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OCX16_RS09970	-	2014632..2015888 (-)	1257	WP_001793428.1	aminopeptidase	-
OCX16_RS09975	-	2015891..2016091 (-)	201	WP_000180460.1	DUF1128 family protein	-
OCX16_RS09980	-	2016238..2016702 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
OCX16_RS09985	-	2016709..2016984 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
OCX16_RS09990	-	2017262..2018473 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
OCX16_RS09995	vraR	2018585..2019214 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
OCX16_RS10000	vraS	2019204..2020247 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
OCX16_RS10005	liaF	2020244..2020945 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
OCX16_RS10010	-	2020960..2021346 (-)	387	WP_001110179.1	hypothetical protein	-
OCX16_RS10015	map	2021563..2022321 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
OCX16_RS10020	-	2022852..2023838 (+)	987	WP_000999713.1	FUSC family protein	-
OCX16_RS10025	-	2024328..2024741 (-)	414	WP_001837236.1	hypothetical protein	-
OCX16_RS10030	-	2024770..2024881 (-)	112	Protein_1942	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=87878 OCX16_RS10000 WP_001017131.1 2019204..2020247(-) (vraS) [Staphylococcus aureus strain 59574]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=87878 OCX16_RS10000 WP_001017131.1 2019204..2020247(-) (vraS) [Staphylococcus aureus strain 59574]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1