Detailed information NTG0878748

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: WOC65_RS06290
• Genome accession: NZ_CP150756
• Coordinates: 1251370..1252644 (-)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus strain TUM22188
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1246370..1257644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC65_RS06275 (WOC65_06270)	-	1248655..1248747 (+)	93	WP_001789987.1	hypothetical protein	-
WOC65_RS06280 (WOC65_06275)	-	1248727..1249632 (-)	906	WP_000184370.1	transglycosylase domain-containing protein	-
WOC65_RS06285 (WOC65_06280)	tyrS	1250014..1251276 (+)	1263	WP_000186029.1	tyrosine--tRNA ligase	-
WOC65_RS06290 (WOC65_06285)	htrA	1251370..1252644 (-)	1275	WP_001279338.1	S1C family serine protease	Regulator
WOC65_RS06295 (WOC65_06290)	-	1252816..1253433 (+)	618	WP_000287588.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
WOC65_RS06300 (WOC65_06295)	nagE	1253561..1255027 (+)	1467	WP_000276362.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
WOC65_RS06305 (WOC65_06300)	-	1255134..1256264 (+)	1131	WP_000721707.1	HAD family hydrolase	-
WOC65_RS06310 (WOC65_06305)	-	1256225..1256320 (-)	96	WP_031789489.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=878748 WOC65_RS06290 WP_001279338.1 1251370..1252644(-) (htrA) [Staphylococcus aureus strain TUM22188]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=878748 WOC65_RS06290 WP_001279338.1 1251370..1252644(-) (htrA) [Staphylococcus aureus strain TUM22188]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTCGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACTATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTCAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37