Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   RI106_RS02390 Genome accession   NZ_CP134071
Coordinates   447621..448595 (+) Length   324 a.a.
NCBI ID   WP_000697227.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 4233     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 442621..453595
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RI106_RS02355 (RI106_02355) rpmG 443081..443230 (+) 150 WP_001265709.1 50S ribosomal protein L33 -
  RI106_RS02360 (RI106_02360) - 443439..443978 (+) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  RI106_RS02365 (RI106_02365) - 443990..445453 (+) 1464 WP_001017867.1 rhomboid family intramembrane serine protease -
  RI106_RS02370 (RI106_02370) - 445434..445637 (+) 204 WP_000087561.1 YqgQ family protein -
  RI106_RS02375 (RI106_02375) - 445634..446620 (+) 987 WP_000161314.1 ROK family glucokinase -
  RI106_RS02380 (RI106_02380) - 446620..446949 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  RI106_RS02385 (RI106_02385) - 446946..447569 (+) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  RI106_RS02390 (RI106_02390) comGA 447621..448595 (+) 975 WP_000697227.1 competence type IV pilus ATPase ComGA Machinery gene
  RI106_RS02395 (RI106_02395) comGB 448567..449637 (+) 1071 WP_000776406.1 competence type IV pilus assembly protein ComGB Machinery gene
  RI106_RS02400 (RI106_02400) comGC 449651..449962 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  RI106_RS02405 (RI106_02405) comGD 449940..450386 (+) 447 WP_310745934.1 competence type IV pilus minor pilin ComGD Machinery gene
  RI106_RS02410 (RI106_02410) comGE 450373..450672 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  RI106_RS02415 (RI106_02415) comGF 450590..451087 (+) 498 WP_001829055.1 competence type IV pilus minor pilin ComGF Machinery gene
  RI106_RS02420 (RI106_02420) - 451184..451330 (+) 147 Protein_444 hypothetical protein -
  RI106_RS02425 (RI106_02425) - 451320..451844 (+) 525 WP_001015123.1 shikimate kinase -
  RI106_RS02430 (RI106_02430) gcvT 452003..453094 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36842.96 Da        Isoelectric Point: 8.8508

>NTDB_id=878673 RI106_RS02390 WP_000697227.1 447621..448595(+) (comGA) [Staphylococcus aureus strain 4233]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYLF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQPQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=878673 RI106_RS02390 WP_000697227.1 447621..448595(+) (comGA) [Staphylococcus aureus strain 4233]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCTTTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACCACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGTATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.383

100

0.994
  comGA Staphylococcus aureus N315

99.383

100

0.994