Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   WOC45_RS12745 Genome accession   NZ_CP150752
Coordinates   2568428..2569141 (-) Length   237 a.a.
NCBI ID   WP_123089530.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TUM22458     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2563428..2574141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WOC45_RS12710 (WOC45_12710) sph 2563430..2564254 (-) 825 Protein_2501 sphingomyelin phosphodiesterase -
  WOC45_RS12715 (WOC45_12715) - 2564311..2565348 (-) 1038 WP_000857180.1 site-specific integrase -
  WOC45_RS12720 (WOC45_12720) - 2565411..2565653 (-) 243 WP_000427213.1 hypothetical protein -
  WOC45_RS12725 (WOC45_12725) - 2565664..2566647 (-) 984 WP_001558608.1 glycosyltransferase family 2 protein -
  WOC45_RS12730 (WOC45_12730) - 2566747..2566929 (-) 183 WP_000694772.1 hypothetical protein -
  WOC45_RS12735 (WOC45_12735) - 2567133..2567474 (-) 342 WP_000591749.1 hypothetical protein -
  WOC45_RS12740 (WOC45_12740) - 2567480..2568412 (-) 933 WP_000759682.1 exonuclease domain-containing protein -
  WOC45_RS12745 (WOC45_12745) irvR 2568428..2569141 (-) 714 WP_123089530.1 XRE family transcriptional regulator Regulator
  WOC45_RS12750 (WOC45_12750) - 2569104..2569278 (+) 175 Protein_2509 transcriptional regulator -
  WOC45_RS12755 (WOC45_12755) - 2569275..2569538 (+) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  WOC45_RS12760 (WOC45_12760) - 2569554..2569769 (+) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  WOC45_RS12765 (WOC45_12765) - 2569758..2570087 (-) 330 WP_000128909.1 hypothetical protein -
  WOC45_RS12770 (WOC45_12770) - 2570138..2570890 (+) 753 WP_001148605.1 phage antirepressor KilAC domain-containing protein -
  WOC45_RS12775 (WOC45_12775) - 2570906..2571103 (+) 198 WP_001148856.1 hypothetical protein -
  WOC45_RS12780 (WOC45_12780) - 2571090..2571470 (-) 381 WP_000762521.1 DUF2513 domain-containing protein -
  WOC45_RS12785 (WOC45_12785) - 2571525..2571848 (+) 324 WP_001120201.1 DUF771 domain-containing protein -
  WOC45_RS12790 (WOC45_12790) - 2571845..2572006 (+) 162 WP_000048129.1 DUF1270 family protein -
  WOC45_RS12795 (WOC45_12795) - 2572101..2572403 (+) 303 WP_000165371.1 DUF2482 family protein -
  WOC45_RS12800 (WOC45_12800) - 2572408..2572668 (+) 261 WP_000291510.1 DUF1108 family protein -
  WOC45_RS12805 (WOC45_12805) - 2572677..2572940 (+) 264 WP_001205732.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27016.60 Da        Isoelectric Point: 5.2068

>NTDB_id=878622 WOC45_RS12745 WP_123089530.1 2568428..2569141(-) (irvR) [Staphylococcus aureus strain TUM22458]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDNLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=878622 WOC45_RS12745 WP_123089530.1 2568428..2569141(-) (irvR) [Staphylococcus aureus strain TUM22458]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTATGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACAATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.571

100

0.397