Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   RE424_RS08540 Genome accession   NZ_CP134047
Coordinates   1726323..1727009 (-) Length   228 a.a.
NCBI ID   WP_078093055.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 21SAU_AGRO3     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1721323..1732009
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RE424_RS08520 rpsT 1722237..1722488 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  RE424_RS08525 holA 1722533..1723507 (-) 975 WP_023914719.1 DNA polymerase III subunit delta -
  RE424_RS08530 comEC 1723564..1725765 (-) 2202 WP_023914721.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  RE424_RS08535 - 1725770..1726231 (-) 462 WP_000439693.1 ComE operon protein 2 -
  RE424_RS08540 comEA 1726323..1727009 (-) 687 WP_078093055.1 ComEA family DNA-binding protein Machinery gene
  RE424_RS08545 - 1727049..1727765 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  RE424_RS08550 rsfS 1727768..1728121 (-) 354 WP_001088022.1 ribosome silencing factor -
  RE424_RS08555 yqeK 1728122..1728706 (-) 585 WP_103254185.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  RE424_RS08560 nadD 1728696..1729265 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  RE424_RS08565 yhbY 1729268..1729558 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  RE424_RS08570 aroE 1729562..1730368 (-) 807 WP_000666748.1 shikimate dehydrogenase -
  RE424_RS08575 yqeH 1730382..1731482 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25788.51 Da        Isoelectric Point: 9.5275

>NTDB_id=878335 RE424_RS08540 WP_078093055.1 1726323..1727009(-) (comEA) [Staphylococcus aureus strain 21SAU_AGRO3]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFEEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=878335 RE424_RS08540 WP_078093055.1 1726323..1727009(-) (comEA) [Staphylococcus aureus strain 21SAU_AGRO3]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTGAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.684

100

0.987
  comEA Staphylococcus aureus N315

97.807

100

0.978