Detailed information NTG0878184

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: RDV49_RS09725
• Genome accession: NZ_CP133988
• Coordinates: 2013611..2014693 (-)
• Length: 360 a.a.
• NCBI ID: WP_003005896.1
• Uniprot ID: A0AAX4AX27
• Organism: Streptococcus parasanguinis strain B-1756
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2008611..2019693

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV49_RS09700 (RDV49_09700)	-	2009830..2010564 (-)	735	WP_003005910.1	response regulator	-
RDV49_RS09705 (RDV49_09705)	msrB	2010623..2011744 (-)	1122	WP_003005907.1	peptide-methionine (R)-S-oxide reductase MsrB	-
RDV49_RS09710 (RDV49_09710)	-	2011756..2012316 (-)	561	WP_037608329.1	redoxin family protein	-
RDV49_RS09715 (RDV49_09715)	-	2012373..2012711 (-)	339	WP_003005903.1	hypothetical protein	-
RDV49_RS09720 (RDV49_09720)	ccdA2	2012738..2013448 (-)	711	WP_003005901.1	thiol-disulfide oxidoreductase-associated membrane protein CcdA2	-
RDV49_RS09725 (RDV49_09725)	sepM	2013611..2014693 (-)	1083	WP_003005896.1	SepM family pheromone-processing serine protease	Regulator
RDV49_RS09730 (RDV49_09730)	coaD	2014677..2015165 (-)	489	WP_003005894.1	pantetheine-phosphate adenylyltransferase	-
RDV49_RS09735 (RDV49_09735)	rsmD	2015155..2015694 (-)	540	WP_037607783.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
RDV49_RS09740 (RDV49_09740)	asnA	2015942..2016934 (-)	993	WP_003005888.1	aspartate--ammonia ligase	-
RDV49_RS09745 (RDV49_09745)	-	2017095..2017772 (+)	678	WP_037607780.1	XRE family transcriptional regulator	-
RDV49_RS09750 (RDV49_09750)	-	2017775..2019187 (+)	1413	WP_003005881.1	Y-family DNA polymerase	-
RDV49_RS09755 (RDV49_09755)	-	2019184..2019555 (+)	372	WP_003005879.1	hypothetical protein	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 39030.63 Da
• Isoelectric Point: 9.2944

>NTDB_id=878184 RDV49_RS09725 WP_003005896.1 2013611..2014693(-) (sepM) [Streptococcus parasanguinis strain B-1756]
MTQANKPSLPTKKKKGRLKEYRWPIAGVLFLLLLLAAFVIRLPYYIEMPGTAEDIRSVMTVDGKADTKSGSYDFVTVAVK
EATPADLIYAWATPFTDIYSAKDMTGGSSSQEFTRINQFYMETSQNMAIYQGLKTAGKETQMDFLGVYVMQVADDSTFKG
ILNIADTVTGVNGKTFKSSKELIDYVGSQKIGDPVSVTYIEDGQTKTADGKIIKLSNGKNGIGISLIDRTEAKGDVPVQF
ATQGIGGPSAGMMFSLAIYTQVADPDLRQGRHIAGTGTINQDGTVGDIGGIDKKVVAADKEGAEIFFAPNNPVSKEEKKA
NPKAKSNYETAKEAAKQIHSKMKIVPVKTLQDAIDYLKKN

Nucleotide

• Length: 1083 bp

>NTDB_id=878184 RDV49_RS09725 WP_003005896.1 2013611..2014693(-) (sepM) [Streptococcus parasanguinis strain B-1756]
ATGACACAAGCGAATAAACCAAGCTTGCCTACAAAAAAGAAAAAAGGACGATTGAAAGAATACCGATGGCCGATTGCAGG
CGTTCTTTTCTTGCTCCTCTTGCTAGCTGCCTTTGTGATTCGCCTTCCCTATTATATTGAGATGCCAGGAACGGCAGAAG
ACATTCGATCGGTCATGACAGTCGATGGAAAAGCGGATACCAAGTCAGGATCCTATGACTTTGTAACCGTGGCAGTGAAA
GAAGCGACCCCGGCTGATTTGATCTATGCTTGGGCGACACCTTTTACAGATATCTACTCTGCCAAGGATATGACAGGTGG
TAGTTCGAGCCAAGAATTTACGCGGATTAACCAATTCTATATGGAAACCTCGCAAAATATGGCTATCTACCAAGGGTTAA
AGACAGCTGGAAAAGAAACCCAGATGGACTTTCTTGGTGTTTATGTCATGCAAGTGGCAGATGATTCGACCTTTAAGGGA
ATCTTGAACATTGCGGATACCGTCACCGGTGTGAATGGCAAGACCTTTAAGAGTTCCAAAGAATTGATTGATTATGTTGG
TTCTCAAAAAATTGGCGATCCCGTTTCAGTGACCTATATTGAGGATGGACAAACCAAGACAGCAGATGGGAAGATCATCA
AATTGTCCAACGGGAAAAACGGAATCGGAATTAGCCTGATCGACCGGACTGAAGCCAAAGGCGATGTTCCTGTCCAATTT
GCGACTCAAGGGATTGGTGGACCAAGTGCCGGCATGATGTTTAGCCTAGCTATCTACACCCAAGTGGCTGATCCAGATCT
TCGTCAGGGACGCCATATTGCAGGGACAGGAACCATTAACCAAGATGGAACGGTTGGCGATATCGGTGGGATTGACAAGA
AAGTCGTCGCAGCCGATAAAGAAGGAGCAGAAATTTTCTTTGCCCCTAATAACCCTGTTTCCAAAGAAGAAAAGAAAGCC
AATCCCAAGGCCAAATCAAACTATGAAACAGCTAAAGAAGCAGCGAAACAAATTCATTCGAAGATGAAAATTGTACCCGT
CAAAACCTTGCAGGATGCCATCGATTATTTGAAAAAGAATTAG

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (246-352)

• PDZ domain (PDZ_2) (145-209)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.526	95	0.575