Detailed information NTG0878087

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: WOC70_RS12270
• Genome accession: NZ_CP150742
• Coordinates: 2454372..2455646 (-)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus strain TUM22707
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2449372..2460646

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC70_RS12255 (WOC70_12255)	-	2451657..2451749 (+)	93	WP_031761401.1	hypothetical protein	-
WOC70_RS12260 (WOC70_12260)	-	2451729..2452634 (-)	906	WP_000184370.1	transglycosylase domain-containing protein	-
WOC70_RS12265 (WOC70_12265)	tyrS	2453016..2454278 (+)	1263	WP_000186029.1	tyrosine--tRNA ligase	-
WOC70_RS12270 (WOC70_12270)	htrA	2454372..2455646 (-)	1275	WP_001279338.1	trypsin-like peptidase domain-containing protein	Regulator
WOC70_RS12275 (WOC70_12275)	-	2455818..2456435 (+)	618	WP_000287588.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
WOC70_RS12280 (WOC70_12280)	nagE	2456563..2458029 (+)	1467	WP_000276367.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
WOC70_RS12285 (WOC70_12285)	-	2458136..2459266 (+)	1131	WP_000721699.1	HAD family hydrolase	-
WOC70_RS12290 (WOC70_12290)	-	2459227..2459322 (-)	96	WP_031761395.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=878087 WOC70_RS12270 WP_001279338.1 2454372..2455646(-) (htrA) [Staphylococcus aureus strain TUM22707]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=878087 WOC70_RS12270 WP_001279338.1 2454372..2455646(-) (htrA) [Staphylococcus aureus strain TUM22707]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTTAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37