Detailed information NTG0878018

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: WOC52_RS13425
• Genome accession: NZ_CP150739
• Coordinates: 2691423..2692697 (+)
• Length: 424 a.a.
• NCBI ID: WP_001279338.1
• Uniprot ID: A0A0H2XGV4
• Organism: Staphylococcus aureus strain TUM22721
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2686423..2697697

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC52_RS13405 (WOC52_13395)	-	2687747..2687842 (+)	96	WP_001789986.1	hypothetical protein	-
WOC52_RS13410 (WOC52_13400)	-	2687803..2688933 (-)	1131	WP_000721707.1	HAD family hydrolase	-
WOC52_RS13415 (WOC52_13405)	nagE	2689040..2690506 (-)	1467	WP_000276366.1	N-acetylglucosamine-specific PTS transporter subunit IIBC	-
WOC52_RS13420 (WOC52_13410)	-	2690634..2691251 (-)	618	WP_000287588.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
WOC52_RS13425 (WOC52_13415)	htrA	2691423..2692697 (+)	1275	WP_001279338.1	trypsin-like peptidase domain-containing protein	Regulator
WOC52_RS13430 (WOC52_13420)	tyrS	2692791..2694053 (-)	1263	WP_000186029.1	tyrosine--tRNA ligase	-
WOC52_RS13435 (WOC52_13425)	-	2694435..2695340 (+)	906	WP_000184370.1	transglycosylase domain-containing protein	-
WOC52_RS13440 (WOC52_13430)	-	2695320..2695412 (-)	93	WP_001789987.1	hypothetical protein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 45802.98 Da
• Isoelectric Point: 9.9696

>NTDB_id=878018 WOC52_RS13425 WP_001279338.1 2691423..2692697(+) (htrA) [Staphylococcus aureus strain TUM22721]
MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALLVLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSK
KFGTVHEMIKSVSPTIVGVINMQKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSVTSGIISASERTIDAETTGGNTK
VSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAATQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIP
EEEREQLHTDREDGIYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKEVKVKLKQQ
KEQPKRQSRSERQSPGQGDRDFFR

Nucleotide

• Length: 1275 bp

>NTDB_id=878018 WOC52_RS13425 WP_001279338.1 2691423..2692697(+) (htrA) [Staphylococcus aureus strain TUM22721]
ATGTCAGATTTTAATCATACAGATCATTCTACAACAAACCATAGCCAAACACCTAGATACAGAAGACCTAAATTTCCATG
GTTTAAAACAGTCATCGTTGCATTGATTGCTGGAATTATTGGTGCACTTCTAGTACTTGGTATAGGCAAAGTATTAAATA
GTACAATTTTAAATAAAGATGGTTCAACTGTTCAGACAACAAATAATAAAGGTGGCAATCAATTAGACGGTCAAAGCAAG
AAATTCGGTACCGTTCATGAAATGATAAAATCTGTCTCCCCTACAATTGTTGGAGTTATTAACATGCAAAAAGCATCAAG
TGTAGACGACTTATTAAAAGGCAAATCATCTAAACCATCTGAAGCTGGAGTAGGTTCAGGTGTTATCTATCAAATAAACA
ACAATTCAGCTTATATCGTTACAAACAATCATGTTATTGATGGCGCAAATGAAATTAGAGTCCAATTACATAATAAAAAA
CAAGTTAAAGCGAAATTAGTTGGTAAAGATGCAGTAACTGATATTGCTGTACTTAAAATTGAAAATACAAAAGGTATTAA
AGCGATTCAATTTGCCAACTCTTCAAAAGTACAAACTGGCGATAGCGTATTCGCAATGGGTAACCCATTAGGATTACAAT
TTGCTAACTCTGTAACATCTGGTATCATTTCAGCAAGCGAACGTACGATTGACGCTGAGACAACTGGTGGCAATACAAAA
GTTAGCGTTCTTCAAACAGATGCTGCTATTAACCCAGGTAACTCAGGTGGCGCATTAGTAGATATTAATGGTAATTTAGT
TGGTATTAACTCAATGAAAATTGCTGCGACACAAGTTGAAGGTATCGGGTTTGCTATTCCAAGTAATGAAGTTAAAGTAA
CAATTGAACAACTTGTAAAACATGGTAAAATTGACCGCCCTTCGATTGGTATTGGTTTAATTAATTTGAAAGATATTCCT
GAAGAAGAGCGCGAGCAACTTCATACTGATAGAGAAGACGGTATTTATGTCGCCAAAGCTGATAGTGATATTGATCTTAA
AAAAGGTGATATTATTACAGAAATTGATGGCAAGAAAATTAAAGATGATGTTGATTTAAGAAGCTATTTATATGAAAATA
AAAAACCTGGTGAATCAGTCACTGTTACCGTTATCCGTGATGGTAAAACAAAAGAAGTTAAAGTGAAATTAAAACAACAA
AAAGAACAACCAAAACGTCAAAGCCGATCAGAACGTCAATCACCTGGCCAAGGCGATAGAGATTTCTTTAGATAA

Domains

Predicted by InterProScan.

• Trypsin-like peptidase domain (Trypsin_2) (125-269)

• PDZ domain (PDZ_2) (307-397)

3D structure

• AlphaFold DB: A0A0H2XGV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	39.055	94.811	0.37