Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   OCX11_RS10670 Genome accession   NZ_AP024726
Coordinates   2127133..2127849 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 59482     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2122133..2132849
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCX11_RS10640 - 2122349..2122975 (+) 627 WP_000522384.1 nitroreductase family protein -
  OCX11_RS10645 - 2123336..2124121 (+) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  OCX11_RS14355 hld 2124720..2124800 (-) 81 WP_000046023.1 delta-hemolysin -
  OCX11_RS10655 - 2125090..2125653 (+) 564 WP_001105705.1 accessory gene regulator AgrB -
  OCX11_RS10660 agrD 2125657..2125797 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  OCX11_RS10665 agrC 2125822..2127114 (+) 1293 WP_172576662.1 quorum-sensing sensor histidine kinase AgrC -
  OCX11_RS10670 agrA 2127133..2127849 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  OCX11_RS10675 - 2127921..2128030 (+) 110 Protein_2070 hypothetical protein -
  OCX11_RS10680 - 2128218..2129177 (-) 960 WP_117201054.1 carbohydrate kinase -
  OCX11_RS10685 - 2129174..2130529 (-) 1356 Protein_2072 sucrose-6-phosphate hydrolase -
  OCX11_RS10690 - 2130529..2131003 (-) 475 Protein_2073 LacI family DNA-binding transcriptional regulator -
  OCX11_RS10695 - 2131186..2132436 (-) 1251 WP_001052267.1 ammonium transporter -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=87792 OCX11_RS10670 WP_000688492.1 2127133..2127849(+) (agrA) [Staphylococcus aureus strain 59482]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=87792 OCX11_RS10670 WP_000688492.1 2127133..2127849(+) (agrA) [Staphylococcus aureus strain 59482]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment