Detailed information NTG0877754

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: RIM63_RS02880
• Genome accession: NZ_CP133952
• Coordinates: 592643..594895 (-)
• Length: 750 a.a.
• NCBI ID: WP_317584760.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain HT321
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 587643..599895

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RIM63_RS02865 (RIM63_02865)	ileS	588223..591021 (+)	2799	WP_317584757.1	isoleucine--tRNA ligase	-
RIM63_RS02870 (RIM63_02870)	-	591684..591986 (-)	303	WP_012515246.1	DUF1827 family protein	-
RIM63_RS02875 (RIM63_02875)	-	592048..592494 (-)	447	WP_317584759.1	NUDIX hydrolase	-
RIM63_RS02880 (RIM63_02880)	clpE	592643..594895 (-)	2253	WP_317584760.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
RIM63_RS02885 (RIM63_02885)	-	595177..595407 (+)	231	WP_037579069.1	DUF1797 family protein	-
RIM63_RS02890 (RIM63_02890)	-	595883..596926 (-)	1044	WP_317584762.1	LPXTG cell wall anchor domain-containing protein	-
RIM63_RS02895 (RIM63_02895)	-	597279..597962 (+)	684	WP_164335036.1	amino acid ABC transporter permease	-
RIM63_RS02900 (RIM63_02900)	-	597964..598701 (+)	738	WP_012678294.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 750 a.a.
• Molecular weight: 83687.10 Da
• Isoelectric Point: 5.9313

>NTDB_id=877754 RIM63_RS02880 WP_317584760.1 592643..594895(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain HT321]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGHNGGGHNGYRPNQAQPAQDTNKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
PGVGKTAVVEGLAQKIVDGDVPQKLQAKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAGA
VGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQS
AIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDYERAAYFRDQIAKYKE
MQAQKLDEQDTPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNRP
IGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLD
EIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMNR
FDGIIEFKPLSKDNLLHIVHLMLDDVNHRLAHNNIHLDVTQKVKEKLVELGYNPKMGARPLRRTIQDHIEDAITDFYLEH
PAEKDLRAVLTSNGHIMIKPVVKSQAKQAD

Nucleotide

• Length: 2253 bp

>NTDB_id=877754 RIM63_RS02880 WP_317584760.1 592643..594895(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain HT321]
ATGCTTTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAATGGAAAGCAAAGACAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATTTTAGGAGGCTACAATGGCAATCAAAAGG
CGCAGCAGCCTTCTCAAAATCCTTTCTTTGATGACTTTTTTGGTGACCTGAACAATTTTAGAGCCTTCGGTCAATTGCCT
AATACACCACCTACCCAATCAGGAGGCCATAATGGCGGAGGTCACAATGGCTACCGTCCCAATCAAGCCCAGCCAGCACA
GGACACTAACAAGGGCTTGCTTGAGGAATTTGGCATTAATATTACTGAAATGGCCAAGCGTGGTGATATTGATCCTGTCA
TCGGACGTGACGATGAGATTATCCGCGTAATTGAGATTCTCAATCGCCGAACGAAAAATAATCCTGTCCTAATCGGTGAG
CCTGGAGTTGGTAAAACCGCTGTCGTTGAAGGCCTTGCTCAAAAAATTGTTGATGGCGATGTGCCACAAAAGCTACAGGC
TAAGCAGGTTATTCGTCTTGATGTGGTTAGCCTCGTTCAGGGAACAGGTATTCGCGGCCAATTTGAAGAGCGCATGCAAA
AGCTCATGGAGGAGATCCGTAAACGTCATGACGTTATCCTTTTTATTGATGAAATCCATGAAATTGTCGGAGCCGGGGCA
GTTGGTGATGGCAGTATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGCCAC
CACTCTCAATGAATACCGCATTATCGAAAAGGACGCAGCTCTCGAACGACGCATGCAGCCGGTTAAGGTAGATGAGCCCT
CGGTTGAAGAAACAATCACTATCCTAAAAGGAATCCAAGCCAAATACGAGGACTATCACCATGTCAAATATAGCCAGTCA
GCTATCGAAGCAGCCGCCAACCTATCCAATCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTACTAGA
TGAGGCTGGCTCAAAAATGAACCTAACCCTTAACTTTGTTGACCCAAAAGACATCGACAAGCGTTTGATTGAGGCAGAAA
ACCTTAAGGCACAAGCCACACGTGATGAAGATTATGAGCGAGCAGCCTACTTCCGCGATCAAATCGCCAAATACAAAGAA
ATGCAGGCTCAAAAGCTAGATGAGCAGGATACTCCAATCATTACCGATAAGACCATTGAAGCAATCGTTGAGCAAAAAAC
CAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTAGCCGCCGATCTCAAAAAGCACGTTA
TCGGTCAAGACGATGCTGTTGATAAAATTGCAAAGGCAATCCGTCGCAATCGTGTTGGACTTGGAGCGCCAAATCGTCCT
ATCGGCTCCTTCCTCTTTGTTGGACCGACTGGTGTCGGAAAAACAGAGCTTTCCAAGCAATTAGCTATTGAGCTTTTTGG
CTCTGCTGATAATATGATTCGCTTTGACATGTCTGAATATATGGAAAAGCATGCTGTGGCTAAGCTTGTAGGTGCCCCTC
CAGGCTACGTTGGCTATGAGGAGGCAGGGCAGTTAACAGAACAGGTACGCCGCAACCCTTACTCGCTCATTTTGTTAGAT
GAGATTGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGGCGATTAACCGACGGACAAGG
ACGGACCGTTAGCTTTAAGGATACTATTATCATCATGACATCAAATGCCGGCACCGGCAAAACAGAAGCTTCAGTAGGCT
TTGGCGCTGCTAGAGAAGGGCGGACAAATTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGTCCCGAGTTCATGAACCGT
TTTGATGGCATTATTGAGTTTAAGCCACTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGTTAA
TCACCGCCTTGCTCACAATAACATTCACCTTGATGTCACCCAAAAGGTCAAAGAAAAGCTCGTTGAGCTAGGCTATAATC
CTAAAATGGGCGCAAGGCCTTTGCGCCGCACGATTCAGGACCACATTGAAGATGCCATTACCGACTTCTACCTTGAGCAC
CCAGCAGAAAAAGACCTGCGAGCTGTCCTGACCTCTAATGGACACATCATGATCAAGCCTGTAGTTAAGTCTCAGGCAAA
GCAGGCAGACTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (156-269)

• AAA domain (Cdc48 subfamily) (AAA_2) (479-642)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (650-724)

• AAA lid domain (AAA_lid_9) (294-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.195	99.067	0.844
clpE	Streptococcus pneumoniae Rx1	82.228	100	0.827
clpE	Streptococcus pneumoniae D39	82.228	100	0.827
clpE	Streptococcus pneumoniae R6	82.228	100	0.827
clpE	Streptococcus pneumoniae TIGR4	82.095	100	0.825
clpC	Lactococcus lactis subsp. cremoris KW2	75.766	100	0.759
clpC	Bacillus subtilis subsp. subtilis str. 168	50.299	89.333	0.449
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.077	84.4	0.397
clpC	Streptococcus pneumoniae Rx1	47.981	82.533	0.396
clpC	Streptococcus pneumoniae D39	47.981	82.533	0.396
clpC	Streptococcus pneumoniae TIGR4	47.819	82.533	0.395
clpC	Streptococcus mutans UA159	47.182	82.8	0.391
clpC	Streptococcus thermophilus LMD-9	46.349	84	0.389
clpC	Streptococcus thermophilus LMG 18311	46.032	84	0.387