Detailed information NTG0877628

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: WOC72_RS10095
• Genome accession: NZ_CP150731
• Coordinates: 2033904..2036513 (+)
• Length: 869 a.a.
• NCBI ID: WP_000353955.1
• Uniprot ID: Q6GAV1
• Organism: Staphylococcus aureus strain TUM22744
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2028904..2041513

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WOC72_RS10080 (WOC72_10080)	-	2030093..2030917 (-)	825	WP_001182436.1	Cof-type HAD-IIB family hydrolase	-
WOC72_RS10085 (WOC72_10085)	-	2031031..2031339 (+)	309	WP_000390575.1	metal-sulfur cluster assembly factor	-
WOC72_RS10090 (WOC72_10090)	-	2031887..2033701 (+)	1815	WP_001044230.1	acyltransferase family protein	-
WOC72_RS10095 (WOC72_10095)	clpC	2033904..2036513 (+)	2610	WP_000353955.1	ATP-dependent chaperone ClpB	Regulator
WOC72_RS10100 (WOC72_10100)	-	2036572..2037441 (-)	870	WP_001047066.1	LysR family transcriptional regulator	-
WOC72_RS10105 (WOC72_10105)	-	2037551..2038696 (+)	1146	WP_000619360.1	LeuA family protein	-
WOC72_RS10110 (WOC72_10110)	-	2038680..2039321 (+)	642	WP_000404422.1	L-threonylcarbamoyladenylate synthase	-
WOC72_RS10115 (WOC72_10115)	-	2039314..2040432 (+)	1119	WP_234726153.1	MFS transporter	-
WOC72_RS10120 (WOC72_10120)	-	2040416..2040931 (+)	516	WP_000695342.1	YbhB/YbcL family Raf kinase inhibitor-like protein	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98303.44 Da
• Isoelectric Point: 4.6833

>NTDB_id=877628 WOC72_RS10095 WP_000353955.1 2033904..2036513(+) (clpC) [Staphylococcus aureus strain TUM22744]
MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQ
YGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEAL
AKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELD
LSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYRE
YIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATI
RTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLDE
SRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETER
EKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSE
YMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIM
TSNIGSQVLLENVKETGEITESTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIE
VSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE

Nucleotide

• Length: 2610 bp

>NTDB_id=877628 WOC72_RS10095 WP_000353955.1 2033904..2036513(+) (clpC) [Staphylococcus aureus strain TUM22744]
ATGGATATAAATAAAATGACATATGCTGTTCAAAGTGCTTTACAACAAGCAGTTGAACTGAGTCAGCAACATAAATTACA
AAATATAGAAATTGAGGCAATTTTAAGCGCTGCCTTAAATGAAAGTGAAAGCTTATATAAAAGTATTTTAGAACGAGCAA
ATATTGAGGTAGATCAATTAAACAAAGCTTATGAAGACAAACTAAACACGTATGCATCTGTAGAAGGTGACAATATACAA
TATGGTCAATATATTAGCCAACAAGCAAACCAATTGATAACTAAGGCTGAATCATACATGAAAGAATATGAAGATGAATA
TATTTCAATGGAGCATATTTTACGTTCGGCAATGGACATTGATCAAACAACAAAACATTATATAAATAATAAAGTAGAAG
TTATCAAAGAAATTATTAAAAAAGTAAGAGGGGGAAATCACGTGACATCACAAAATCCAGAAGTTAATTACGAAGCATTA
GCTAAATATGGCCGCGACTTAGTAGAAGAAGTTAGACAAGGTAAAATGGATCCTGTTATAGGAAGAGATGAAGAAATTCG
AAATACGATTCGTATTTTAAGTCGTAAAACTAAAAACAACCCTGTGCTCATTGGTGAACCAGGTGTTGGTAAAACTGCAA
TTGTTGAAGGATTAGCGCAACGTATAGTTAAGAAAGATGTGCCAGAATCATTATTAGATAAAACTGTTTTTGAGTTAGAT
TTAAGCGCATTAGTAGCGGGCGCTAAATATCGTGGTGAATTTGAAGAGAGATTAAAAGCAGTCCTAAAAGAAGTTAAAGA
GTCTGATGGTAGAATTATATTATTTATTGATGAAATCCATATGCTTGTAGGTGCTGGTAAAACAGATGGTGCCATGGATG
CAGGCAACATGCTAAAACCAATGTTAGCACGAGGAGAGTTACATTGTATTGGTGCAACAACTTTAAATGAATATCGAGAA
TATATTGAAAAAGATTCGGCATTAGAGCGTCGTTTCCAAAAAGTAGCAGTTAGTGAGCCTGATGTTGAAGATACAATTTC
AATTTTACGTGGTTTAAAAGAACGATATGAAGTGTATCATGGTGTGCGTATTCAAGATAGAGCCTTAGTTGCTGCCGCTG
AATTGTCTGATCGTTACATCACTGATCGTTTTTTACCAGATAAAGCGATTGATTTAGTTGACCAAGCATGTGCAACAATT
CGTACGGAAATGGGATCAAATCCAACTGAATTGGATCAAGTTAATAGACGTGTCATGCAATTAGAAATTGAAGAAAGCGC
ACTTAAAAATGAATCTGACAATGCGAGCAAACAGAGATTACAAGAACTACAAGAAGAGCTTGCCAATGAAAAAGAGAAAC
AAGCAGCACTTCAATCTCGTGTAGAATCAGAAAAAGAAAAAATAGCAAATTTACAAGAAAAACGTGCGCAACTAGATGAA
AGTAGACAAGCGTTGGAAGATGCACAAACAAATAACAATTTAGAAAAAGCTGCTGAACTACAATATGGAACAATTCCTCA
ATTGGAAAAAGAACTTAGAGAATTAGAGGATAATTTCCAAGATGAGCAAGGTGAAGATACAGATCGAATGATTCGTGAAG
TTGTAACAGACGAAGAAATTGGCGATATTGTCAGCCAATGGACAGGCATACCAGTTTCAAAATTAGTTGAAACAGAACGT
GAAAAATTACTTCACTTAAGTGACATCTTGCATAAACGTGTTGTAGGTCAAGATAAAGCGGTTGACCTGGTTTCAGATGC
AGTAGTTAGAGCAAGAGCAGGTATTAAAGATCCAAACAGACCTATTGGTAGTTTCTTATTCCTAGGTCCAACTGGAGTAG
GTAAAACTGAATTAGCTAAATCATTAGCTGCATCATTATTTGATTCTGAAAAACATATGATTCGTATTGATATGAGTGAA
TATATGGAAAAACATGCAGTATCAAGATTGATAGGGGCACCTCCAGGATATATTGGACATGATGAAGGGGGTCAATTAAC
TGAAGCGGTTCGTCGTAATCCATACTCAGTTATTTTATTAGATGAGGTTGAAAAAGCGCATACTGACGTCTTTAATGTAT
TATTGCAAATTTTAGATGAAGGCCGTTTAACTGATTCTAAAGGACGTAGCGTTGATTTTAAAAATACTATTATTATTATG
ACAAGTAATATTGGATCTCAAGTTTTATTAGAAAACGTAAAAGAGACTGGTGAAATTACAGAATCAACAGAAAAAGCTGT
TATGACAAGTTTAAATGCATATTTCAAACCAGAAATTTTGAATCGTATGGATGATATCGTATTATTTAAACCATTATCTA
TTGATGACATGAGTATGATTGTAGATAAAATCTTAACGCAATTAAATATAAGATTATTAGAACAACGAATCTCAATTGAA
GTTTCTGATGATGCTAAAGCTTGGCTAGGTCAAGAAGCTTATGAACCTCAATACGGTGCAAGACCATTAAAACGTTTTGT
ACAACGCCAAATTGAAACACCATTAGCACGTATGATGATTAAAGAGGGATTCCCAGAAGGTACAACGATTAAAGTTAATT
TAAATTCAGACAATAACTTAACGTTTAATGTTGAAAAAATTCATGAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-443)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-121)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

• ATPase family associated with various cellular activities (AAA) (AAA) (202-334)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (772-852)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-766)

3D structure

• AlphaFold DB: Q6GAV1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	44.289	98.734	0.437
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	39.863	100	0.403