Detailed information NTG0087754

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: OCX22_RS13775
• Genome accession: NZ_AP024723
• Coordinates: 2744635..2745522 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain 59458
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2739635..2750522

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OCX22_RS13745	-	2739654..2739746 (+)	93	WP_010956583.1	hypothetical protein	-
OCX22_RS13750 (SA59458_26110)	-	2739854..2740351 (-)	498	WP_001065268.1	glutathione peroxidase	-
OCX22_RS13755 (SA59458_26120)	-	2740361..2740621 (-)	261	WP_001791974.1	hypothetical protein	-
OCX22_RS13760	-	2741003..2741116 (-)	114	Protein_2675	hypothetical protein	-
OCX22_RS13765 (SA59458_26130)	-	2741775..2743775 (-)	2001	WP_000776740.1	ABC transporter permease	-
OCX22_RS13770 (SA59458_26140)	-	2743772..2744527 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
OCX22_RS13775 (SA59458_26150)	braS	2744635..2745522 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
OCX22_RS13780 (SA59458_26160)	braR	2745533..2746198 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
OCX22_RS13785 (SA59458_26170)	-	2746224..2746424 (-)	201	WP_000604727.1	hypothetical protein	-
OCX22_RS13790 (SA59458_26180)	-	2746622..2748046 (+)	1425	WP_000953748.1	alkaline phosphatase	-
OCX22_RS14575	-	2748106..2748207 (-)	102	WP_000731972.1	SE2200 family small protein	-
OCX22_RS13800 (SA59458_26190)	-	2748329..2748784 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
OCX22_RS13805 (SA59458_26210)	-	2749029..2749790 (-)	762	Protein_2684	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=87754 OCX22_RS13775 WP_000143417.1 2744635..2745522(-) (braS) [Staphylococcus aureus strain 59458]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=87754 OCX22_RS13775 WP_000143417.1 2744635..2745522(-) (braS) [Staphylococcus aureus strain 59458]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99