Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   RF668_RS07770 Genome accession   NZ_CP133787
Coordinates   1484858..1486330 (+) Length   490 a.a.
NCBI ID   WP_043735252.1    Uniprot ID   A0AAX4A423
Organism   Lactococcus cremoris strain KCKM 0438     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1479858..1491330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RF668_RS07740 (RF668_07740) - 1480326..1481162 (+) 837 WP_043735256.1 metallophosphoesterase -
  RF668_RS07745 (RF668_07745) - 1481255..1482166 (+) 912 WP_043735255.1 CHAP domain-containing protein -
  RF668_RS07750 (RF668_07750) - 1482402..1482764 (+) 363 WP_043735253.1 TIGR02328 family protein -
  RF668_RS07755 (RF668_07755) - 1483088..1483333 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  RF668_RS07760 (RF668_07760) - 1483466..1483996 (+) 531 WP_011834860.1 DUF177 domain-containing protein -
  RF668_RS07765 (RF668_07765) covR 1484153..1484845 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  RF668_RS07770 (RF668_07770) covS 1484858..1486330 (+) 1473 WP_043735252.1 HAMP domain-containing histidine kinase Regulator
  RF668_RS07775 (RF668_07775) - 1486516..1487757 (+) 1242 WP_309558501.1 ammonium transporter -
  RF668_RS07780 (RF668_07780) - 1487840..1488181 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  RF668_RS07785 (RF668_07785) murD 1488349..1489698 (+) 1350 WP_043735249.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  RF668_RS07790 (RF668_07790) murG 1489941..1491014 (+) 1074 WP_309558503.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55917.77 Da        Isoelectric Point: 4.7011

>NTDB_id=876890 RF668_RS07770 WP_043735252.1 1484858..1486330(+) (covS) [Lactococcus cremoris strain KCKM 0438]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMANDPTNDFKPIEI
ESGDEIEELAHVYNNMMLKMKAYLEQQDRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALARLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=876890 RF668_RS07770 WP_043735252.1 1484858..1486330(+) (covS) [Lactococcus cremoris strain KCKM 0438]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATTAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAGTTATTATATTCAACTAATCGACATGATTTTG
GATTTCAAAAGCAAGGCAATAATGAAATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAATGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATAATATGATGCTGAAAATGAAAGCATATCTTGAACAGCA
AGATCGGTTTGTCTCTGACGTTTCACATGAATTAAGGACTCCGCTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGGAAAAATGATCCAGAGGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTGGCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTACTCGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTTGCTCGTTTAGCCGAAAATTATCAAGGGGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATGTGA

Domains

Predicted by InterproScan.

HAMP domain (HAMP)

(208-258)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

ArlS sensor domain (ArlS_N)

(54-185)

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945