Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   RF668_RS03950 Genome accession   NZ_CP133787
Coordinates   775029..776060 (+) Length   343 a.a.
NCBI ID   WP_043736755.1    Uniprot ID   A0AAX4A758
Organism   Lactococcus cremoris strain KCKM 0438     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 770029..781060
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RF668_RS03930 (RF668_03930) lmrP 771259..772485 (+) 1227 WP_043736759.1 multidrug efflux MFS transporter LmrP -
  RF668_RS03935 (RF668_03935) - 772568..773785 (+) 1218 WP_043736758.1 MFS transporter -
  RF668_RS03940 (RF668_03940) rsmD 773958..774497 (+) 540 WP_011836079.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  RF668_RS03945 (RF668_03945) coaD 774545..775045 (+) 501 WP_042748015.1 pantetheine-phosphate adenylyltransferase -
  RF668_RS03950 (RF668_03950) sepM 775029..776060 (+) 1032 WP_043736755.1 SepM family pheromone-processing serine protease Regulator
  RF668_RS03955 (RF668_03955) - 776380..776493 (+) 114 WP_082231670.1 KxxxW-cyclized peptide pheromone -
  RF668_RS03960 (RF668_03960) kwcM 776561..777880 (+) 1320 WP_043736753.1 KxxxW cyclic peptide radical SAM maturase -
  RF668_RS03965 (RF668_03965) - 777964..779013 (+) 1050 WP_228764266.1 MFS transporter -
  RF668_RS03970 (RF668_03970) - 779065..779907 (+) 843 WP_043736750.1 Rgg/GadR/MutR family transcriptional regulator -
  RF668_RS03975 (RF668_03975) - 780130..780273 (+) 144 WP_155723358.1 hypothetical protein -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 37388.00 Da        Isoelectric Point: 9.8558

>NTDB_id=876862 RF668_RS03950 WP_043736755.1 775029..776060(+) (sepM) [Lactococcus cremoris strain KCKM 0438]
MNKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGMMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALTYLEK

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=876862 RF668_RS03950 WP_043736755.1 775029..776060(+) (sepM) [Lactococcus cremoris strain KCKM 0438]
ATGAACAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGCCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGGAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTCTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACTGCACAAAATACAGCCGTTTATCAGGCATTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATTGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATGATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTGCCCGATTCAGGCACCAAAAAAGAAAGTAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACCATTCAAGACGCTTTAACTTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(229-339)

PDZ domain (PDZ_2)

(135-193)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

48.406

100

0.487