Detailed information NTG0876463

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: RGQ10_RS14265
• Genome accession: NZ_CP133760
• Coordinates: 2854546..2855709 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain F37
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2849546..2860709

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RGQ10_RS14235 (RGQ10_14235)	-	2849811..2850230 (-)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-
RGQ10_RS14240 (RGQ10_14240)	comFC	2850304..2850993 (-)	690	WP_197535984.1	ComF family protein	Machinery gene
RGQ10_RS14245 (RGQ10_14245)	-	2850999..2851283 (-)	285	WP_014419011.1	late competence development ComFB family protein	-
RGQ10_RS14250 (RGQ10_14250)	comFA	2851341..2852726 (-)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
RGQ10_RS14255 (RGQ10_14255)	-	2852834..2853682 (-)	849	WP_003151387.1	DegV family protein	-
RGQ10_RS14260 (RGQ10_14260)	degU	2853780..2854469 (-)	690	WP_111927758.1	two-component system response regulator DegU	Regulator
RGQ10_RS14265 (RGQ10_14265)	degS	2854546..2855709 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
RGQ10_RS14270 (RGQ10_14270)	-	2855932..2856579 (+)	648	WP_007614107.1	YigZ family protein	-
RGQ10_RS14275 (RGQ10_14275)	-	2856584..2857798 (+)	1215	WP_014419013.1	LCP family protein	-
RGQ10_RS14280 (RGQ10_14280)	-	2857888..2858964 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
RGQ10_RS14285 (RGQ10_14285)	-	2859097..2860293 (-)	1197	WP_014419014.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=876463 RGQ10_RS14265 WP_007407484.1 2854546..2855709(-) (degS) [Bacillus velezensis strain F37]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=876463 RGQ10_RS14265 WP_007407484.1 2854546..2855709(-) (degS) [Bacillus velezensis strain F37]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951