Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   RGC87_RS14170 Genome accession   NZ_CP133660
Coordinates   2811421..2812770 (+) Length   449 a.a.
NCBI ID   WP_002486033.1    Uniprot ID   -
Organism   Staphylococcus aureus strain JH4322     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2806345..2822745 2811421..2812770 within 0


Gene organization within MGE regions


Location: 2806345..2822745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RGC87_RS14155 (RGC87_14155) - 2807859..2808905 (+) 1047 WP_001042023.1 hypothetical protein -
  RGC87_RS14160 (RGC87_14160) ssb 2809098..2809394 (+) 297 WP_000273823.1 cassette chromosome ssDNA-binding protein -
  RGC87_RS14165 (RGC87_14165) cch1 2809394..2811187 (+) 1794 WP_000079474.1 cassette chromosome replicative helicase -
  RGC87_RS14170 (RGC87_14170) ccrA 2811421..2812770 (+) 1350 WP_002486033.1 cassette chromosome recombinase CcrA Machinery gene
  RGC87_RS14175 (RGC87_14175) ccrB 2812792..2814420 (+) 1629 WP_001186608.1 cassette chromosome recombinase CcrB Machinery gene
  RGC87_RS14180 (RGC87_14180) - 2814942..2815292 (+) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  RGC87_RS14185 (RGC87_14185) - 2815379..2815690 (+) 312 WP_000700851.1 DUF960 family protein -
  RGC87_RS14190 (RGC87_14190) - 2815705..2816211 (+) 507 WP_001092189.1 DUF1643 domain-containing protein -
  RGC87_RS14195 (RGC87_14195) - 2816260..2817858 (+) 1599 Protein_2763 IS1182 family transposase -
  RGC87_RS14200 (RGC87_14200) - 2817955..2819154 (-) 1200 WP_073392450.1 IS110-like element ISSep2 family transposase -
  RGC87_RS14205 (RGC87_14205) - 2819421..2819666 (-) 246 Protein_2765 type I restriction enzyme endonuclease domain-containing protein -
  RGC87_RS14210 (RGC87_14210) - 2819653..2820639 (-) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  RGC87_RS14215 (RGC87_14215) mecA 2820736..2822745 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52614.32 Da        Isoelectric Point: 9.9100

>NTDB_id=875702 RGC87_RS14170 WP_002486033.1 2811421..2812770(+) (ccrA) [Staphylococcus aureus strain JH4322]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQLTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQTKQTSSDNQLKQKIKCPCCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTLEDKVLKV
CQDFYQDQHIYVKIKNAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFRKQMQSLHQQPQRITSISEHQIQHTIQ
NIIQKRFTLNILYPYIETIHIAKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=875702 RGC87_RS14170 WP_002486033.1 2811421..2812770(+) (ccrA) [Staphylococcus aureus strain JH4322]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAATTAACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACGTACCATGTTCATATCTTAAGCGTACATGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGACTCAAGCTTAATATCTTCATCAGTTTAGCCGAACTTGAATCGGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACACATGCACCTTTTGGTTACGATTATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGCCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
ATGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAATATGAATGCTTCACGCTTTGTCTGTGATTTCAAAGGCATCAATGCACAGACATTGGAAGATAAAGTATTAAAAGTG
TGCCAAGACTTTTATCAAGACCAACATATCTACGTAAAAATTAAAAATGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAGCATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTTA
GAAAACAAATGCAATCATTACATCAACAACCACAACGCATCACATCCATCAGTGAGCATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTGCGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCAATTGCATAA

Domains

Predicted by InterproScan.

Recombinase (Recombinase)

(169-250)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)

Resolvase, N terminal domain (Resolvase)

(4-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

95.546

100

0.955
  ccrA Staphylococcus aureus COL

74.833

100

0.748