Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   WID27_RS29755 Genome accession   NZ_CP149796
Coordinates   6882842..6885898 (+) Length   1018 a.a.
NCBI ID   WP_070203724.1    Uniprot ID   A0A1E7LKP7
Organism   Streptomyces sp. F41     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 6877842..6890898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WID27_RS29740 (WID27_29740) - 6880102..6881121 (+) 1020 WP_029395071.1 TerC family protein -
  WID27_RS29745 (WID27_29745) - 6881291..6881947 (-) 657 WP_070203722.1 MBL fold metallo-hydrolase -
  WID27_RS29750 (WID27_29750) - 6881976..6882665 (-) 690 WP_070203723.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  WID27_RS29755 (WID27_29755) uvrA 6882842..6885898 (+) 3057 WP_070203724.1 excinuclease ABC subunit UvrA Machinery gene
  WID27_RS29760 (WID27_29760) - 6886137..6886565 (+) 429 WP_019764263.1 Rieske (2Fe-2S) protein -
  WID27_RS29765 (WID27_29765) - 6886715..6887641 (-) 927 WP_339153381.1 hypothetical protein -
  WID27_RS29770 (WID27_29770) - 6887869..6888486 (+) 618 WP_070203725.1 papain-like cysteine protease family protein -
  WID27_RS29775 (WID27_29775) - 6888491..6889408 (+) 918 WP_070203726.1 hypothetical protein -

Sequence

Protein


Download         Length: 1018 a.a.        Molecular weight: 111263.59 Da        Isoelectric Point: 8.3382

>NTDB_id=875272 WID27_RS29755 WP_070203724.1 6882842..6885898(+) (uvrA) [Streptomyces sp. F41]
MADRLIVRGAREHNLKNVSLDLPRDSLIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSSYARQFLGQMDKPDVDFIEGL
SPAVSIDQKSTSRNPRSTVGTITEVYDYLRLLFARIGKPHCPECGRPIARQSPQAIVDKVLGLPEGSRFQVLSPLVRERK
GEFVDLFADLQTKGYSRARVDGATIQLSEPPTLKKQEKHTIEVVVDRLTVKDSAKRRLTDSVETALGLSGGMVVLDFVDL
PEDDPERERMYSEHLYCAYDDLSFEELEPRSFSFNSPFGACPDCTGIGTRMEVDPELIVPDEEKSLDEGAIHPWSHGHTK
EYFGRLIGALAKALGFRTDIPWAGLPQRAKKALLHGHKIQTEVRYRNRYGRERAYTTPAFEGAVQFVKRRHTEAESDSSR
ERFEGYMREVPCPTCEGSRLKPIVLAVTVMEKSIAEVSAMSISECAEFLGRLKLNARDKKIAERVLKEVNERLKFLVDVG
LDYLSLNRAAGTLSGGEAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNHRLIETLVRLRDMGNTLIVVEHDEDTIKVA
DWVVDIGPGAGEHGGKVVHSGSLKELLSNKESVTGQYLSGKRSIPTPDVRRPVDPARSLTVHGARENNLHDIDVSFPLGV
LTAVTGVSGSGKSTLVNDILYTHLARELNGAKSVPGRHTRVDGDDLVDKVVHVDQSPIGRTPRSNPATYTGVFDHVRKLF
AETMEAKVRGYLPGRFSFNVKGGRCENCSGDGTIKIEMNFLPDVYVPCEVCHGARYNRETLEVHYKGKSIAEVLDMPIEE
GLEFFEAVPAIARHLRTLNDVGLGYVRLGQSAPTLSGGEAQRVKLASELQKRSTGRTVYVLDEPTTGLHFEDISKLITVL
SGLVDKGNSVIVIEHNLDVIKTADWVIDMGPEGGNGGGMVVAEGTPEQVASVPASHTGKFLQGILDADRISEAAVPSGRG
GARKTATAARKTAAAKKTAAPKKAATATKKATATKATATRKTAATKATAKKATRARKA

Nucleotide


Download         Length: 3057 bp        

>NTDB_id=875272 WID27_RS29755 WP_070203724.1 6882842..6885898(+) (uvrA) [Streptomyces sp. F41]
GTGGCCGACCGTCTCATCGTCCGTGGCGCGCGCGAGCACAACCTGAAGAACGTCTCGCTCGATCTCCCCCGTGACTCCCT
CATCGTCTTCACCGGGCTCTCCGGGTCGGGTAAGTCGTCCCTCGCGTTCGACACGATCTTCGCCGAGGGCCAGCGGCGTT
ACGTGGAGTCCCTCTCCTCGTACGCCCGGCAGTTCCTCGGCCAGATGGACAAGCCGGACGTCGATTTCATCGAGGGTCTC
TCCCCGGCCGTCTCCATCGACCAGAAGTCGACCTCGCGCAACCCGCGCTCGACGGTCGGCACCATCACGGAGGTCTACGA
CTACCTCCGCCTGCTCTTCGCCCGGATCGGCAAGCCGCACTGCCCCGAGTGCGGCCGCCCCATCGCCCGCCAGTCGCCGC
AGGCCATCGTGGACAAGGTCCTCGGCCTGCCCGAGGGCAGCCGCTTCCAGGTCCTCTCGCCGCTCGTCCGCGAGCGCAAG
GGCGAGTTCGTCGACCTCTTCGCCGACCTCCAGACCAAGGGGTACAGCCGCGCCCGGGTCGACGGCGCCACCATCCAGCT
CTCCGAGCCGCCCACGCTCAAGAAGCAGGAGAAGCACACCATCGAGGTGGTCGTCGACCGCCTCACCGTCAAGGACAGCG
CCAAGCGCCGCCTCACCGACTCGGTGGAGACCGCCCTCGGTCTCTCCGGCGGCATGGTCGTCCTCGACTTCGTCGACCTC
CCCGAGGACGACCCCGAGCGCGAGCGGATGTATTCGGAGCACCTCTACTGCGCCTACGACGACCTCTCCTTCGAGGAGCT
GGAGCCGCGCTCCTTCTCCTTCAACTCGCCCTTCGGCGCCTGCCCGGACTGCACCGGCATCGGCACCCGCATGGAGGTCG
ACCCGGAGCTGATCGTCCCGGACGAGGAGAAGTCCCTCGACGAAGGGGCGATCCACCCCTGGTCCCACGGCCACACCAAG
GAGTACTTCGGCCGGCTGATCGGCGCCCTCGCCAAGGCCCTCGGCTTCCGTACGGACATCCCCTGGGCCGGACTGCCGCA
GCGCGCCAAGAAGGCCCTGCTCCACGGCCACAAGATCCAGACCGAGGTCCGCTACCGCAACCGGTACGGGCGCGAGCGCG
CCTACACCACGCCCGCCTTCGAGGGCGCGGTGCAGTTCGTCAAGCGGCGCCACACCGAGGCCGAGAGCGACTCCAGCCGC
GAGCGCTTCGAGGGCTACATGCGCGAGGTGCCCTGCCCCACCTGTGAGGGCTCCCGGCTCAAGCCGATCGTCCTCGCGGT
GACGGTGATGGAGAAGTCCATCGCCGAGGTCTCCGCCATGTCGATCAGCGAGTGCGCCGAGTTCCTCGGCCGCCTCAAGC
TGAACGCCCGCGACAAGAAGATCGCCGAGCGGGTCCTCAAGGAGGTCAACGAGCGGCTGAAGTTCCTGGTCGACGTCGGC
CTGGACTACCTCTCGCTCAACCGCGCGGCCGGCACCCTCTCCGGCGGCGAGGCCCAGCGCATCCGGCTCGCCACCCAGAT
CGGCTCCGGCCTGGTCGGCGTGCTGTACGTCCTGGACGAGCCGTCCATCGGCCTCCACCAGCGCGACAACCACCGGCTGA
TCGAGACCTTGGTCCGCCTCCGCGACATGGGCAACACGCTCATCGTCGTCGAGCACGACGAGGACACCATCAAGGTGGCC
GACTGGGTCGTCGACATCGGCCCCGGCGCCGGTGAGCACGGCGGCAAGGTCGTCCACTCCGGCTCGCTCAAGGAACTGCT
CTCCAACAAGGAGTCGGTCACCGGGCAGTATCTGTCCGGCAAGCGGTCCATCCCGACCCCGGACGTCCGCCGCCCGGTCG
ACCCGGCCCGCAGCCTCACCGTGCACGGCGCCCGCGAGAACAACCTCCACGACATCGACGTCTCCTTCCCGCTCGGCGTG
CTCACCGCCGTCACCGGAGTCTCCGGCTCCGGGAAGTCGACCCTGGTCAACGACATCCTCTACACCCACCTGGCCCGCGA
GCTGAACGGCGCCAAGTCGGTCCCCGGCCGCCACACCCGGGTCGACGGCGACGACCTCGTCGACAAGGTGGTCCACGTCG
ACCAGTCCCCGATCGGCCGGACCCCCCGGTCCAACCCGGCGACGTACACCGGAGTCTTCGACCACGTCCGCAAGCTCTTC
GCGGAGACGATGGAGGCGAAGGTGCGCGGCTATCTGCCGGGCCGCTTCTCCTTCAACGTCAAGGGCGGCCGCTGCGAGAA
CTGCTCCGGCGACGGCACCATCAAGATCGAGATGAACTTCCTGCCGGACGTCTACGTCCCGTGCGAGGTCTGCCACGGTG
CGCGCTACAACCGGGAGACCCTGGAGGTCCACTACAAGGGCAAGTCCATCGCCGAGGTGCTGGACATGCCGATCGAGGAG
GGCCTGGAGTTCTTCGAGGCCGTCCCTGCCATCGCCCGCCACCTCCGTACGCTCAACGACGTGGGTCTGGGGTACGTCCG
GCTCGGCCAGTCCGCGCCGACCCTCTCCGGCGGTGAGGCGCAGCGCGTCAAGCTGGCGAGCGAGCTGCAGAAGCGCTCCA
CCGGGCGCACGGTCTACGTCCTGGACGAGCCGACCACCGGTCTCCACTTCGAGGACATCAGCAAGCTGATCACCGTCCTC
TCCGGCCTGGTCGACAAGGGCAACTCGGTGATCGTCATCGAGCACAACCTGGACGTCATCAAGACCGCGGACTGGGTCAT
CGACATGGGCCCAGAAGGCGGCAACGGCGGTGGCATGGTCGTGGCCGAGGGCACGCCGGAGCAGGTCGCCTCGGTCCCCG
CCAGCCACACCGGGAAGTTCCTCCAGGGGATCCTGGACGCGGACCGGATCAGCGAGGCCGCGGTGCCGTCGGGGCGGGGT
GGGGCTCGTAAGACCGCCACCGCCGCCCGGAAGACCGCCGCAGCGAAGAAGACGGCGGCGCCGAAGAAGGCCGCCACCGC
CACCAAGAAGGCCACGGCGACCAAGGCCACGGCGACCAGGAAGACGGCGGCCACCAAGGCCACCGCGAAGAAGGCGACGC
GCGCCCGCAAGGCGTGA

Domains

Predicted by InterProScan.

UvrA interaction domain (UvrA_inter)

(131-238)

UvrA DNA-binding domain (UvrA_DNA-bind)

(294-404)

ABC transporter (ABC_tran)

(629-865)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E7LKP7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

56.481

93.222

0.527
  uvrA Streptococcus pneumoniae TIGR4

56.481

93.222

0.527
  uvrA Streptococcus pneumoniae D39

56.481

93.222

0.527