Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WID27_RS16805 Genome accession   NZ_CP149796
Coordinates   3904100..3904759 (+) Length   219 a.a.
NCBI ID   WP_070199420.1    Uniprot ID   A0A1E7M1K2
Organism   Streptomyces sp. F41     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3899100..3909759
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WID27_RS16785 (WID27_16785) - 3900022..3901389 (-) 1368 WP_208623657.1 hypothetical protein -
  WID27_RS16790 (WID27_16790) - 3901386..3901982 (-) 597 WP_070199423.1 ankyrin repeat domain-containing protein -
  WID27_RS16795 (WID27_16795) - 3902029..3902586 (-) 558 WP_070199422.1 heme-binding protein -
  WID27_RS16800 (WID27_16800) - 3902817..3904103 (+) 1287 WP_339152489.1 sensor histidine kinase -
  WID27_RS16805 (WID27_16805) vraR 3904100..3904759 (+) 660 WP_070199420.1 response regulator transcription factor Regulator
  WID27_RS16810 (WID27_16810) - 3904805..3905689 (-) 885 WP_339152490.1 hypothetical protein -
  WID27_RS16815 (WID27_16815) - 3905792..3906289 (+) 498 WP_028419539.1 hypothetical protein -
  WID27_RS16820 (WID27_16820) - 3906395..3907096 (-) 702 WP_339152491.1 pentapeptide repeat-containing protein -
  WID27_RS16825 (WID27_16825) - 3907198..3908403 (+) 1206 WP_339152492.1 NAD(P)-binding protein -
  WID27_RS16830 (WID27_16830) - 3908604..3909605 (+) 1002 WP_070199416.1 zinc-binding dehydrogenase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 23081.45 Da        Isoelectric Point: 5.1153

>NTDB_id=875245 WID27_RS16805 WP_070199420.1 3904100..3904759(+) (vraR) [Streptomyces sp. F41]
MTGEAIASPAPSPSPVRILLCDDHVVVRAGLLALLGSEPDIEVVGEAGSGEEAVVLAARLTPDVVLMDLQLGAGIDGVEA
TRRIAADGTVHVLVLTTYDTDADITRAIEAGATGYLLKAERPEELFAAIRSAAQGRTTLSAPVASRVMARMRSPRPTLTD
RERDILAQLSQGLGNRDIARALFISEATVKTHLGRIYDKLGVDTRAGAVSVAKEQRLLP

Nucleotide


Download         Length: 660 bp        

>NTDB_id=875245 WID27_RS16805 WP_070199420.1 3904100..3904759(+) (vraR) [Streptomyces sp. F41]
ATGACCGGCGAGGCAATCGCGTCCCCCGCCCCCTCTCCCTCCCCCGTACGCATCCTGCTCTGCGACGACCACGTGGTCGT
CCGCGCCGGGCTGCTGGCCCTCCTCGGCAGCGAACCGGACATCGAGGTCGTCGGGGAGGCGGGCAGCGGCGAGGAGGCCG
TGGTGCTCGCCGCCCGCCTCACCCCCGACGTCGTCCTCATGGACCTCCAGCTCGGTGCGGGCATCGACGGCGTGGAGGCC
ACCCGCCGCATCGCCGCCGACGGCACGGTCCACGTCCTGGTGCTGACCACGTACGACACGGACGCCGACATCACCCGCGC
CATCGAGGCCGGGGCCACCGGCTATCTGCTGAAGGCGGAGCGCCCGGAGGAGCTGTTCGCCGCCATCCGCTCGGCCGCCC
AGGGCCGCACCACCCTCTCGGCACCCGTCGCCAGCCGGGTCATGGCCCGGATGCGCAGCCCCCGCCCGACCCTCACCGAC
CGCGAACGCGACATCCTGGCCCAGCTCTCCCAGGGCCTGGGCAACCGGGACATCGCCCGCGCCCTGTTCATCAGCGAGGC
CACGGTCAAGACCCACCTGGGCCGCATCTACGACAAGCTCGGCGTCGACACCCGCGCGGGCGCGGTCTCGGTGGCCAAGG
AACAGCGGCTGCTGCCCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(157-212)

Response regulator receiver domain (Response_reg)

(18-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E7M1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.462

94.977

0.365