Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   WHL52_RS03100 Genome accession   NZ_CP149576
Coordinates   588557..589198 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain DSM 10     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 583557..594198
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WHL52_RS03070 ydfE 584752..585375 (-) 624 WP_003243530.1 flavin reductase family protein -
  WHL52_RS03075 ydfF 585465..586145 (+) 681 WP_003244115.1 winged helix-turn-helix domain-containing protein -
  WHL52_RS03080 ydfG 586225..586668 (-) 444 WP_003242768.1 carboxymuconolactone decarboxylase family protein -
  WHL52_RS03085 - 586754..586933 (-) 180 WP_010886421.1 hypothetical protein -
  WHL52_RS03090 - 586930..587073 (-) 144 WP_003243880.1 hypothetical protein -
  WHL52_RS03095 ydfH 587341..588564 (+) 1224 WP_010886422.1 two-component system sensor histidine kinase YdfH -
  WHL52_RS03100 vraR 588557..589198 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  WHL52_RS03105 ydfJ 589314..591488 (+) 2175 WP_003243548.1 MMPL family transporter -
  WHL52_RS03110 cesA 591900..592802 (-) 903 WP_003242638.1 carboxylesterase -
  WHL52_RS03115 ydfK 593004..593693 (-) 690 WP_003242513.1 DUF554 domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=874901 WHL52_RS03100 WP_003244318.1 588557..589198(+) (vraR) [Bacillus subtilis strain DSM 10]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=874901 WHL52_RS03100 WP_003244318.1 588557..589198(+) (vraR) [Bacillus subtilis strain DSM 10]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTAGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAAGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362