Detailed information NTG0874398

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: RDV50_RS08690
• Genome accession: NZ_CP133462
• Coordinates: 1815733..1817958 (+)
• Length: 741 a.a.
• NCBI ID: WP_137041007.1
• Uniprot ID: -
• Organism: Neisseria subflava strain LMG 5313
• Function: DNA processing; DNA transport into the cytoplasm (predicted from homology) DNA processing DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1804638..1824831	1815733..1817958	within	0

Gene organization within MGE regions

Location: 1804638..1824831

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV50_RS08660 (RDV50_08660)	tssA	1804638..1805696 (-)	1059	WP_137041012.1	type VI secretion system protein TssA	-
RDV50_RS08665 (RDV50_08665)	-	1805701..1806255 (-)	555	WP_137041011.1	TagF domain-containing protein	-
RDV50_RS08670 (RDV50_08670)	-	1806589..1810818 (+)	4230	WP_244284879.1	DUF6531 domain-containing protein	-
RDV50_RS08675 (RDV50_08675)	-	1810852..1811352 (+)	501	WP_137041010.1	SMI1/KNR4 family protein	-
RDV50_RS08680 (RDV50_08680)	-	1811546..1814563 (+)	3018	WP_309004587.1	RHS repeat-associated core domain-containing protein	-
RDV50_RS08685 (RDV50_08685)	-	1814579..1815250 (+)	672	WP_049344263.1	hypothetical protein	-
RDV50_RS08690 (RDV50_08690)	comA	1815733..1817958 (+)	2226	WP_137041007.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
RDV50_RS08695 (RDV50_08695)	-	1818262..1818882 (+)	621	WP_137041006.1	phosphoribosylanthranilate isomerase	-
RDV50_RS08700 (RDV50_08700)	-	1818919..1819521 (+)	603	WP_137041005.1	DNA glycosylase	-
RDV50_RS08705 (RDV50_08705)	-	1819526..1819936 (+)	411	WP_137041004.1	hypothetical protein	-
RDV50_RS08710 (RDV50_08710)	trpB	1820050..1821252 (+)	1203	WP_137041003.1	tryptophan synthase subunit beta	-
RDV50_RS08715 (RDV50_08715)	-	1821447..1822352 (+)	906	WP_137041002.1	DMT family transporter	-
RDV50_RS08720 (RDV50_08720)	bioA	1822405..1823694 (+)	1290	WP_137041001.1	adenosylmethionine--8-amino-7-oxononanoate transaminase	-
RDV50_RS08725 (RDV50_08725)	bioD	1823691..1824347 (+)	657	WP_137041000.1	dethiobiotin synthase	-
RDV50_RS08730 (RDV50_08730)	-	1824337..1824831 (+)	495	WP_137040999.1	chorismate lyase	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 80917.49 Da
• Isoelectric Point: 9.8683

>NTDB_id=874398 RDV50_RS08690 WP_137041007.1 1815733..1817958(+) (comA) [Neisseria subflava strain LMG 5313]
MAWRFMLPAWVVGVVLSFALPFVPPWWAWLSVIIGVLALCRRFAVAWLVLAVCVGMVFGVWQTGLVLAGQWPVGEAAAKV
LTVEVADMSRDDGRRVQFAARAWDERGQEFDLILSDYQRRDWAVGSRWSVPVRVKPVIGEVNVRGLNRETWALANGIDGM
GTLGRDRKLVRQGGGFGLANMRDAVSRSWQRTGDKYPEFSDGIGLMRALSIGEQSALRPPLWQAFRPLGLTHLVSISGLH
VTMVAVLFAWLIKRIFRSLPWIPAKPRVWILAGGVAGALFYALLAGFSVPTQRSVLMLAAFAWAWWRGSGGSGWTAWWQA
LAVVLLLDPLAVLAVGTWLSFGLVAALIWASSGRLKESGWSLAVRGQWAATVLSVVLLGYLFASLPLLSPLVNALAIPWF
SWVLTPLALLGSVFPFELVQLVAAFLAEYTLRGLVWLATVSPEFAVAAAPVLLLVLAMMAALLLLLPKGMGLKPWACLVL
LGFVFYRPAKLEEGVARVTVMDAGQGLSVLIQTRNRNLLFDTGTEQVAQTGIVPSLNAMGVRRLDSLILSHHDIDHDGGF
QSVAAVGTDKLLAGQPEFYPNAEFCQEDKWRWDGVDFELLRPSENTGKEDNDQSCVLRVVANGKALLITGDLGVKGEAGL
IEKYGNALYSQVLILGHHGSSTASSGSFLHTVSPQYAVASSGYANAYKHPTVAVQNRVRAHGITLLRTDLSGALVFALGQ
GDIFQGRLKKDKFYWQKKPFE

Nucleotide

• Length: 2226 bp

>NTDB_id=874398 RDV50_RS08690 WP_137041007.1 1815733..1817958(+) (comA) [Neisseria subflava strain LMG 5313]
ATGGCGTGGCGGTTTATGTTGCCTGCTTGGGTGGTGGGTGTAGTGCTTTCGTTTGCGTTGCCGTTTGTACCGCCATGGTG
GGCTTGGTTGTCTGTAATCATTGGCGTGCTTGCGTTGTGTCGAAGATTTGCTGTAGCTTGGTTGGTGCTGGCCGTCTGTG
TAGGCATGGTGTTTGGAGTGTGGCAGACCGGGCTGGTTTTGGCTGGTCAATGGCCTGTGGGGGAGGCGGCGGCTAAAGTT
TTGACGGTTGAAGTGGCGGATATGTCGCGTGATGATGGTCGGCGTGTGCAGTTTGCGGCAAGGGCTTGGGATGAACGTGG
GCAGGAATTTGATTTGATATTGTCGGATTATCAGCGGCGTGATTGGGCGGTGGGCAGTCGGTGGTCTGTACCGGTGCGGG
TAAAGCCGGTGATCGGTGAAGTGAATGTGCGCGGTTTGAACCGTGAAACATGGGCTTTGGCCAATGGTATCGATGGCATG
GGTACTTTGGGGCGCGACAGAAAACTCGTGCGGCAAGGTGGCGGTTTCGGTTTGGCTAATATGCGTGATGCGGTAAGCCG
GAGTTGGCAGAGAACAGGGGATAAGTATCCTGAGTTTTCAGACGGCATAGGGCTGATGCGTGCTTTGAGTATTGGCGAGC
AGTCGGCATTGCGGCCGCCTTTGTGGCAGGCATTCCGTCCTTTGGGGCTGACGCACTTGGTCAGTATTTCGGGCTTGCAT
GTGACGATGGTGGCAGTATTGTTTGCCTGGCTGATTAAGCGAATTTTCCGTTCTTTACCGTGGATTCCGGCGAAACCGCG
TGTGTGGATATTGGCCGGCGGTGTTGCCGGTGCTTTGTTTTATGCGCTTTTGGCCGGTTTTTCTGTGCCGACGCAACGCA
GTGTGTTGATGTTGGCTGCGTTTGCATGGGCATGGTGGCGCGGCAGTGGCGGCTCGGGCTGGACGGCGTGGTGGCAGGCT
TTGGCCGTTGTTTTGTTGTTGGACCCGTTGGCTGTATTGGCCGTGGGAACTTGGCTGTCATTCGGTTTGGTTGCTGCTTT
GATTTGGGCTTCATCAGGCCGTCTGAAAGAGTCGGGCTGGAGTTTGGCTGTACGGGGGCAATGGGCAGCGACGGTATTGT
CAGTGGTATTGCTGGGCTATTTGTTTGCTTCGTTACCTTTGCTCAGTCCGTTGGTTAATGCGCTGGCTATTCCTTGGTTT
TCTTGGGTGTTGACGCCGTTGGCTTTGCTGGGTTCGGTTTTCCCGTTTGAGCTTGTTCAGTTGGTAGCGGCATTTTTGGC
GGAATATACTTTACGCGGTTTGGTATGGCTGGCTACGGTATCGCCTGAATTTGCCGTCGCAGCAGCGCCTGTGCTTTTGC
TGGTGTTGGCGATGATGGCGGCTTTGCTGTTATTGTTGCCTAAAGGCATGGGCTTGAAACCTTGGGCATGTTTGGTTTTA
TTGGGTTTTGTGTTTTACCGTCCTGCCAAGTTGGAGGAGGGGGTGGCAAGAGTTACGGTGATGGATGCAGGGCAAGGTTT
GTCGGTATTGATACAAACGCGTAACCGCAATCTTTTGTTTGATACGGGAACGGAACAAGTGGCGCAAACAGGTATTGTGC
CGAGTTTGAACGCTATGGGTGTGCGCCGTTTGGACAGCTTGATTTTGTCGCACCATGATATTGACCATGACGGCGGTTTT
CAGAGTGTAGCGGCTGTCGGTACCGATAAATTGCTTGCCGGACAACCTGAGTTTTATCCGAATGCAGAGTTTTGCCAAGA
AGACAAATGGCGATGGGACGGCGTAGATTTCGAGTTGCTCAGGCCGTCTGAAAATACGGGCAAGGAAGATAACGACCAAA
GCTGCGTATTGCGTGTCGTGGCAAACGGCAAAGCCTTGTTGATAACCGGAGATTTGGGTGTGAAAGGCGAGGCCGGTTTG
ATTGAGAAATACGGCAATGCGCTGTATAGCCAAGTGTTGATATTGGGACATCACGGCAGCAGCACGGCTTCGTCAGGCAG
CTTTTTGCATACGGTTTCGCCACAATATGCCGTGGCATCCAGCGGCTATGCCAATGCCTACAAACATCCGACCGTTGCCG
TACAAAATCGTGTCCGCGCGCACGGCATTACTTTATTGAGAACGGATTTGTCAGGCGCGTTGGTATTTGCTTTGGGACAG
GGCGATATATTTCAAGGCCGTCTGAAAAAGGATAAGTTTTATTGGCAGAAGAAACCGTTTGAGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (209-468)

• Metallo-beta-lactamase superfamily (Lactamase_B) (503-679)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Neisseria gonorrhoeae MS11	69.377	99.595	0.691