Detailed information NTG0874110

Bioinformatically predicted

Overview

• Name: ccrB
• Type: Machinery gene
• Locus tag: RDJ18_RS00260
• Genome accession: NZ_CP133442
• Coordinates: 57263..58891 (-)
• Length: 542 a.a.
• NCBI ID: WP_001186596.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain SA191
• Function: promote SCCmec transfer (predicted from homology) Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
SCCmec	39097..60258	57263..58891	within	0

Gene organization within MGE regions

Location: 39097..60258

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDJ18_RS00165 (RDJ18_00165)	mecA	39097..41106 (-)	2010	WP_001801873.1	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA	-
RDJ18_RS00170 (RDJ18_00170)	mecR1	41203..42960 (+)	1758	WP_000952922.1	beta-lactam sensor/signal transducer MecR1	-
RDJ18_RS00175 (RDJ18_00175)	mecI	42960..43331 (+)	372	Protein_32	mecA-type methicillin resistance repressor MecI	-
RDJ18_RS00180 (RDJ18_00180)	psm-mec	43416..43484 (-)	69	WP_014532405.1	phenol-soluble modulin PSM-mec	-
RDJ18_RS00185 (RDJ18_00185)	-	43804..44952 (+)	1149	WP_000427807.1	ROK family transcriptional regulator	-
RDJ18_RS00190 (RDJ18_00190)	cstB	45066..46400 (-)	1335	Protein_35	persulfide dioxygenase-sulfurtransferase CstB	-
RDJ18_RS00195 (RDJ18_00195)	-	46432..47496 (-)	1065	WP_000438836.1	DsrE/DsrF/DrsH-like family protein	-
RDJ18_RS00200 (RDJ18_00200)	cstR	47632..47892 (+)	261	WP_000220507.1	persulfide-sensing transcriptional repressor CstR	-
RDJ18_RS00205 (RDJ18_00205)	-	47892..48530 (+)	639	Protein_38	sulfite exporter TauE/SafE family protein	-
RDJ18_RS00210 (RDJ18_00210)	-	48804..49421 (-)	618	WP_000562107.1	CadD family cadmium resistance transporter	-
RDJ18_RS00215 (RDJ18_00215)	-	49502..51916 (-)	2415	WP_000378485.1	cadmium-translocating P-type ATPase CadA	-
RDJ18_RS00220 (RDJ18_00220)	-	51909..52274 (-)	366	WP_000159127.1	metalloregulator ArsR/SmtB family transcription factor	-
RDJ18_RS00225 (RDJ18_00225)	-	52512..52889 (-)	378	WP_000361059.1	DUF6262 family protein	-
RDJ18_RS00230 (RDJ18_00230)	-	52896..54787 (-)	1892	Protein_43	site-specific integrase	-
RDJ18_RS00235 (RDJ18_00235)	-	54982..55305 (-)	324	WP_000088091.1	JAB domain-containing protein	-
RDJ18_RS00240 (RDJ18_00240)	-	55298..55504 (-)	207	WP_001077283.1	hypothetical protein	-
RDJ18_RS00245 (RDJ18_00245)	-	55506..56027 (-)	522	WP_000836008.1	DUF1643 domain-containing protein	-
RDJ18_RS00250 (RDJ18_00250)	-	56046..56357 (-)	312	WP_000833212.1	DUF960 family protein	-
RDJ18_RS00255 (RDJ18_00255)	-	56442..56792 (-)	351	WP_000171449.1	SAUGI family uracil-DNA glycosylase inhibitor	-
RDJ18_RS00260 (RDJ18_00260)	ccrB	57263..58891 (-)	1629	WP_001186596.1	cassette chromosome recombinase CcrB	Machinery gene
RDJ18_RS00265 (RDJ18_00265)	ccrA	58912..60258 (-)	1347	WP_000816499.1	cassette chromosome recombinase CcrA	Machinery gene

Sequence

Protein

• Length: 542 a.a.
• Molecular weight: 62274.15 Da
• Isoelectric Point: 9.7334

>NTDB_id=874110 RDJ18_RS00260 WP_001186596.1 57263..58891(-) (ccrB) [Staphylococcus aureus strain SA191]
MQQLKQKRVGIYVRVSTEIQSTEGYSIDGQINQIREYCDFNNFVVVDVYADRGISGKSMNRPELQRLLKDANEGQIDSVM
VYKTNRLARNTSDLLKIVEDLHRQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSIGSVTYILSNPFYVGKIQFAK
YKDWNEKRRKGLNDKPIIAEGKHSPIIIQDLWDKVQLRKKQVSQKPQVHGKGTNLLTGIVHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEKYVMDQILEIVKSDKVINQVLERVNQENKVDIGALNHDIAYKQQQYD
EVSGKLHNLVKTIEDNPDLTSALKATIHQYETQLNDITNQMNQLKQQQNQEKLSYDTKQIAALLQRIFQNIESMDKAQLK
ALYLTVIDRIDIRKDGNHKKQFYVTLKLNNEIIKQLFNNTPLDEVLLSTSSLFLPQTLFLQI

Nucleotide

• Length: 1629 bp

>NTDB_id=874110 RDJ18_RS00260 WP_001186596.1 57263..58891(-) (ccrB) [Staphylococcus aureus strain SA191]
ATGCAACAACTCAAACAAAAACGTGTCGGTATCTATGTTCGTGTATCAACGGAAATCCAAAGTACTGAAGGCTATAGTAT
CGATGGACAAATCAATCAAATTCGAGAATATTGTGATTTCAATAACTTTGTTGTTGTAGATGTATACGCGGATAGAGGTA
TCTCTGGAAAATCTATGAACCGACCAGAACTACAACGTTTGTTAAAAGATGCGAACGAAGGTCAGATTGATTCTGTTATG
GTCTACAAAACAAACCGACTAGCACGTAACACTTCTGACTTACTCAAAATTGTTGAAGACCTTCATCGTCAAAATGTCGA
ATTCTTCAGCTTATCTGAGCGTATGGAAGTCAATACAAGCAGTGGTAAATTGATGCTACAAATTCTAGCGAGTTTTTCAG
AATTTGAAAGAAATAATATTGTCGAAAATGTATTCATGGGTCAAACCCGACGCGCTCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCGGATAGCAAGCATGAACTCATGATAAACCAACATGAAGCGAATATTGTCAAATA
TATATTTGAGTCATATGCTAAAGGCCACGGATATCGTAAAATTGCGAATGCACTCAATCACAAAGGATACGTGACTAAAA
AAGGAAAGCCTTTCAGTATTGGTTCAGTGACCTATATCTTATCTAATCCATTCTATGTTGGTAAAATTCAATTCGCAAAG
TACAAAGATTGGAATGAAAAGCGTCGTAAAGGGCTGAATGATAAACCAATAATAGCTGAAGGTAAGCATTCCCCTATTAT
TATTCAAGACTTATGGGATAAAGTCCAATTACGTAAAAAACAAGTCAGTCAAAAACCTCAAGTCCACGGTAAAGGAACTA
ATCTATTAACAGGTATCGTTCATTGTCCACAATGTGGTGCACCAATGGCAGCTAGTAACACAACGAACACATTGAAAGAT
GGTACCAAGAAGCGAATACGTTATTATTCTTGCAGTAACTTCCGAAACAAAGGCTCAAAAGTATGTTCTGCGAATAGCGT
TAGAGCTGATGTGATTGAGAAATACGTCATGGATCAAATACTCGAAATTGTCAAAAGTGATAAAGTCATTAACCAAGTCT
TAGAACGTGTCAATCAAGAAAATAAAGTCGATATTGGTGCATTGAACCACGATATCGCTTATAAACAACAACAATACGAT
GAAGTCAGCGGGAAACTCCATAATTTAGTTAAAACCATTGAAGATAATCCGGACCTAACATCTGCATTGAAAGCAACTAT
TCATCAATATGAAACACAACTCAATGACATTACAAATCAAATGAATCAACTCAAACAGCAACAAAATCAAGAGAAACTAT
CTTATGATACGAAACAAATCGCTGCCCTATTACAACGAATATTTCAAAATATAGAATCAATGGATAAAGCACAACTCAAA
GCATTATATCTTACAGTCATTGACCGTATTGATATTCGTAAAGACGGTAATCATAAAAAACAGTTCTACGTTACACTAAA
ACTCAATAATGAAATTATTAAACAACTTTTCAATAATACCCCTCTCGACGAAGTGCTCCTCAGCACTTCGTCTTTATTTT
TGCCTCAAACGCTCTTTCTTCAAATCTAA

Domains

Predicted by InterproScan.

• Resolvase, N terminal domain (Resolvase) (11-156)

• Recombinase (Recombinase) (180-280)

• Ogr/Delta-like zinc finger (Ogr_Delta) (301-356)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccrB	Staphylococcus aureus N315	86.531	100	0.865